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CYP27B1 抗体 (C-Term)

CYP27B1 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN951779
发货至: 中国
  • 抗原 See all CYP27B1 抗体
    CYP27B1 (Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1))
    抗原表位
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 479-508, C-Term
    适用
    • 16
    • 9
    • 7
    • 5
    宿主
    • 29
    • 2
    克隆类型
    • 29
    • 2
    多克隆
    标记
    • 16
    • 5
    • 5
    • 4
    • 1
    This CYP27B1 antibody is un-conjugated
    应用范围
    • 19
    • 19
    • 7
    • 7
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    特异性
    Recognizes CYP27B1 (C-term).
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
    免疫原
    KLH conjugated synthetic peptide between 479~508 amino acids from the C-terminal region of Human CYP27B1
    亚型
    Ig Fraction
    Top Product
    Discover our top product CYP27B1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS, 0.09 % (W/V) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CYP27B1 (Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1))
    别名
    CYP27B1 (CYP27B1 产品)
    别名
    cp2b antibody, cyp1 antibody, cyp1alpha antibody, cyp27b antibody, p450c1 antibody, pddr antibody, vdd1 antibody, vddr antibody, vddri antibody, vdr antibody, CP2B antibody, CYP1 antibody, CYP1alpha antibody, CYP27B antibody, P450c1 antibody, PDDR antibody, VDD1 antibody, VDDR antibody, VDDRI antibody, VDR antibody, Cyp40 antibody, Cp2b antibody, Cyp1 antibody, Cyp27b antibody, Pddr antibody, Vdd1 antibody, Vddr antibody, VddrI antibody, Vdr antibody, cytochrome P450 family 27 subfamily B member 1 antibody, cytochrome P450, family 27, subfamily B, polypeptide 1 antibody, cytochrome P450, family 27, subfamily b, polypeptide 1 antibody, cyp27b1 antibody, CYP27B1 antibody, Cyp27b1 antibody
    背景
    CYP27B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I.Synonyms: 25-OHD-1 alpha-hydroxylase, 25-hydroxyvitamin D(3) 1-alpha-hydroxylase, 25-hydroxyvitamin D-1 alpha hydroxylase, CYP1ALPHA, CYP27B, Calcidiol 1-monooxygenase, Cytochrome P450 subfamily XXVIIB polypeptide 1, Cytochrome P450C1 alpha, Cytochrome P450VD1-alpha, Cytochrome p450 27B1, VD3 1A hydroxylase
    基因ID
    1594
    NCBI登录号
    NP_000776
    途径
    Metabolism of Steroid Hormones and Vitamin D
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