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COPS7A 抗体 (C-Term)

COPS7A 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN951662
发货至: 中国
  • 抗原 See all COPS7A 抗体
    COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))
    抗原表位
    • 9
    • 8
    • 6
    • 5
    • 3
    • 3
    • 1
    AA 244-274, C-Term
    适用
    • 45
    • 22
    • 21
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 44
    • 1
    克隆类型
    • 45
    多克隆
    标记
    • 17
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COPS7A antibody is un-conjugated
    应用范围
    • 39
    • 22
    • 19
    • 5
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to COPS7A.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography on Protein A
    免疫原
    KLH conjugated synthetic peptide between 244-274 amino acids from the C-terminal region of human COPS7A
    亚型
    Ig Fraction
    Top Product
    Discover our top product COPS7A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS, 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))
    别名
    COPS7A (COPS7A 产品)
    别名
    D6Ertd35e antibody, CSN7A antibody, COP9 signalosome subunit 7A antibody, COPS7A antibody, Cops7a antibody
    背景
    Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.Synonyms: COP9 signalosome complex subunit 7a, CSN7A, DERP10, Dermal papilla-derived protein 10, JAB1-containing signalosome subunit 7a, SGN7a, Signalosome subunit 7a
    分子量
    30277 Da
    基因ID
    50813
    NCBI登录号
    NP_001157565
    途径
    Cell Division Cycle
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