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TLR9 抗体

TLR9 适用: 人, 小鼠, 大鼠 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN951281
发货至: 中国
  • 抗原 See all TLR9 抗体
    TLR9 (Toll-Like Receptor 9 (TLR9))
    适用
    • 94
    • 39
    • 13
    • 7
    • 7
    • 3
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    • 1
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    人, 小鼠, 大鼠
    宿主
    • 64
    • 33
    • 7
    • 4
    • 1
    克隆类型
    • 72
    • 37
    多克隆
    标记
    • 62
    • 13
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    • 7
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    • 1
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    This TLR9 antibody is un-conjugated
    应用范围
    • 77
    • 49
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    • 23
    • 15
    • 12
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    • 6
    • 5
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    • 3
    • 2
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    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody detects TLR9. Located in the membrane, and highly expressed in spleen, lymph node, tonsil and peripheral blood leukocytes, especially in plasmacytoid pre-dendritic cells. Levels are much lower in monocytes and CD11c+ immature dendritic cells. Also detected in lung and liver (6).
    纯化方法
    Purified
    免疫原
    Peptide corresponding to 15 amino acids near the center of human TLR9
    亚型
    IgG
    Top Product
    Discover our top product TLR9 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline with 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
  • 抗原
    TLR9 (Toll-Like Receptor 9 (TLR9))
    别名
    CD289 / TLR9 (TLR9 产品)
    别名
    CD289 antibody, toll like receptor 9 antibody, toll-like receptor 9 antibody, TLR9 antibody, Tlr9 antibody
    背景
    Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). TLR9 forms a subfamily along with TLR7 and TLR8 that recognize viral RNA and CpG DNA sequences (3) and are localized in intracellular acidic compartments such as the phagolysosome (4). Unlike other TLRs which act through adaptor molecules such as TOLLIP, TIRAP, TRIF, and MyD88 to activate various kinases and transcription factors to respond to potential infection (5), TLR9 is strictly dependent on MyD88 (3).Synonyms: Toll-like receptor 9, UNQ5798/PRO19605
    基因ID
    54106
    NCBI登录号
    NP_059138
    UniProt
    Q9NR96
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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