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- 抗原 See all TEK 抗体
- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
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抗原表位
- AA 19-745
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TEK antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Recognizes TIE-2 (CD202b/TEK)
- 交叉反应 （详细）
- Species reactivity (tested):Human and Mouse.
- 纯化方法
- Protein A Chromatography
- 免疫原
- Highly pure (>95%) recombinant Human soluble TIE-2 (Thr19-Lys745) derived from Insect cells.
- 亚型
- IgG
- Top Product
- Discover our top product TEK Primary Antibody
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anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 66-185) antibody
TEK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A5 unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) antibodyTEK 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 571-748) antibodyTEK 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 3F5B9 unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 758-789) antibodyTEK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 701-800) antibodyTEK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F8 unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 401-550) antibodyTEK 适用: 人, 小鼠, 大鼠, Cow ELISA, FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 286-465) antibodyTEK 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) antibodyTEK 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) antibodyTEK 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 701-800) antibodyTEK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5G6 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 溶解方式
- Centrifuge vial prior to opening. Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
- 缓冲液
- PBS, pH 7.2
- 储存条件
- 4 °C/-20 °C
- 储存方法
- The lyophilized antibody is stable at RT for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C. Avoid repeated freeze-thaw cycles!
- 有效期
- 6 months
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- 抗原
- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
- 别名
- CD202b / TEK (TEK 产品)
- 别名
- TEK antibody, DKFZp469E064 antibody, AA517024 antibody, Cd202b antibody, Hyk antibody, Tie2 antibody, tie-2 antibody, CD202B antibody, TIE-2 antibody, TIE2 antibody, VMCM antibody, VMCM1 antibody, Tie-2 antibody, tie2 antibody, TEK receptor tyrosine kinase antibody, angiopoietin-1 receptor antibody, TEK tyrosine kinase, endothelial antibody, TEK antibody, LOC100408334 antibody, tek antibody, Tek antibody
- 背景
- TIE-1 (tyrosine kinase with Ig and EGF homology domains 1) and TIE-2/TEK comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains and followed by three fibronectin type III-like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region. These receptors are expressed primarily on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis. Human TIE-2 cDNA encodes a 1124 amino acid (aa) residue precursor protein with an 18 residue putative signal peptide, a 727 residue extracellular domain and a 354 residue cytoplasmic domain. Two ligands, angiopoietin-1 (Ang1) and angiopoietin-2 (Ang2), which bind TIE-2 with high affinity have been identified. Ang2 has been reported to act as an antagonist for Ang1. Mice engineered to overexpress Ang2 or to lack Ang1 or TIE-2 display similar angiogenic defects.Synonyms: Angiopoietin-1 receptor, TIE-2, TIE2, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, p140 TEK
- 基因ID
- 7010
- NCBI登录号
- NP_000450
- 途径
- RTK signaling, Growth Factor Binding
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