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Angiopoietin 2 抗体 (N-Term)

ANGPT2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN95113
发货至: 中国
  • 抗原 See all Angiopoietin 2 (ANGPT2) 抗体
    Angiopoietin 2 (ANGPT2)
    抗原表位
    • 15
    • 10
    • 7
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 75
    • 36
    • 26
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 77
    • 10
    • 4
    • 1
    • 1
    • 1
    克隆类型
    • 68
    • 26
    多克隆
    标记
    • 48
    • 10
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Angiopoietin 2 antibody is un-conjugated
    应用范围
    • 64
    • 32
    • 32
    • 13
    • 13
    • 12
    • 10
    • 10
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB)
    特异性
    This antiserum is directed against mouse angiopoietin-2 and shows no reactivity with angiopoietin-1 from mouse-derived proteins. A 75 kDa band is detected when assayed by immunoblot. This reagent cross-reacts with human angiopoietin-2. Partially cross-reactivity is noted with human angiopoietin-1.
    产品特性
    Anti Antiopoietin-2 Antibody recognizes Angiopoietin-2 (Ang-2) that has importance in development of the endothelium through regulation of tyrosine phosphorylation of the membrane receptor Tie-2/Tek. Ang-1 binding to Tie-2/Tek causes phosphorylation of the receptor. Ang-2 competes for this binding and thus blocks receptor phosphorylation. Ang-2 expression occurs at sites of vascular remodelling: dorsal aorta and major aortic branches, ovary, placenta and uterus.
    过滤
    Sterile filtered
    免疫原
    This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide, corresponding to a region near the N-terminus of mouse angiopoietin-2 protein, conjugated to KLH using maleimide.
    Immunogen Type: Peptide
    Top Product
    Discover our top product ANGPT2 Primary Antibody
  • 应用备注
    Angiopoietin 2 Antibody is suitable for western blotting and other antibody based assays. A 1:500 dilution is recommended for western blotting. The reaction of this antiserum directly with cell supernatants may result in high background due to reactivity of components in the serum. This can be alleviated by first immunoprecipitating the antibody:antigen complex and then detecting the antigen. This method results in a very clean, strong signal.
    说明

    Gene Name: ANG-2

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
    有效期
    12 months
  • Câmpean, Karpe, Haas, Atalla, Peters, Rupprecht, Liebner, Acker, Plate, Amann: "Angiopoietin 1 and 2 gene and protein expression is differentially regulated in acute anti-Thy1.1 glomerulonephritis." in: American journal of physiology. Renal physiology, Vol. 294, Issue 5, pp. F1174-84, (2008) (PubMed).

    Davis, Aldrich, Jones, Acheson, Compton, Jain, Ryan, Bruno, Radziejewski, Maisonpierre, Yancopoulos: "Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning." in: Cell, Vol. 87, Issue 7, pp. 1161-9, (1997) (PubMed).

  • 抗原
    Angiopoietin 2 (ANGPT2)
    别名
    Angiopoietin 2 (ANGPT2 产品)
    别名
    AGPT2 antibody, ANG2 antibody, Agpt2 antibody, Ang-2 antibody, Ang2 antibody, ang2 antibody, angpt2 antibody, ANGIOPOIETIN-2 antibody, ANG-2 antibody, ANGPT2 antibody, Angrp antibody, Rnase5b antibody, ANG3 antibody, C11orf2 antibody, C11orf3 antibody, FFR antibody, angiopoietin 2 antibody, angiopoietin 2b antibody, angiogenin, ribonuclease A family, member 2 antibody, VPS51, GARP complex subunit antibody, ANGPT2 antibody, Angpt2 antibody, angpt2b antibody, Ang2 antibody, VPS51 antibody
    背景
    Anti Antiopoietin-2 Antibody recognizes Angiopoietin-2 (Ang-2) that has importance in development of the endothelium through regulation of tyrosine phosphorylation of the membrane receptor Tie-2/Tek. Ang-1 binding to Tie-2/Tek causes phosphorylation of the receptor. Ang-2 competes for this binding and thus blocks receptor phosphorylation. Ang-2 expression occurs at sites of vascular remodelling: dorsal aorta and major aortic branches, ovary, placenta and uterus.
    Synonyms: AGPT 2 antibody, Agpt2 antibody, ANG 2 antibody, ANG2 antibody, Angiopoietin 2a antibody, Angiopoietin 2B antibody, Angiopoietin2 antibody, ANGPT 2 antibody, ANGPT2 antibody, Tie2 ligand antibody
    基因ID
    11601
    UniProt
    O35608
    途径
    RTK signaling
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