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Angiopoietin 1 抗体

ANGPT1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN95109
发货至: 中国
  • 抗原 See all Angiopoietin 1 (ANGPT1) 抗体
    Angiopoietin 1 (ANGPT1)
    适用
    • 89
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    • 6
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    • 1
    • 1
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    • 1
    小鼠
    宿主
    • 96
    • 9
    • 1
    • 1
    克隆类型
    • 89
    • 18
    多克隆
    标记
    • 49
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    • 1
    • 1
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    This Angiopoietin 1 antibody is un-conjugated
    应用范围
    • 87
    • 35
    • 30
    • 16
    • 13
    • 13
    • 12
    • 8
    • 7
    • 5
    • 5
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    Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    Concentration Definition: by Refractometry
    免疫原
    This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide N-Q-R-R-N-P-E-N-G-G-R-R-Y-N-R-I-Q-H-G-Q corresponding to a region (aa 21-40) near the of mouse angiopoietin 1 protein conjugated to KLH using maleimide. A residue of cysteine was added to the amino terminal end to facilitate coupling.
    Top Product
    Discover our top product ANGPT1 Primary Antibody
  • 应用备注
    Suitable for western blotting, Immunohistochemistry (IHC) and other antibody based assays.  A 1:500 dilution is recommended for western blotting.  The reaction of this antiserum directly with cell supernatants may result in high background due to reactivity of components in the serum.  This can be alleviated by first immunoprecipitating the antibody:antigen complex and then detecting the antigen. This method results in a very clean and strong signal.  Both Ang-1 and Ang-2 proteins have predicted molecular weights of approximately 57 kDa and appear on western blots close to their predicted molecular weights.  In some instances additional bands may be seen at approximately 75 kDa which represent highly glycosylated forms of the protein that migrate at a higher apparent molecular weight.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    85 mg/mL
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • Egginton, Hussain, Hall-Jones, Chaudhry, Syeda, Glen: "Shear stress-induced angiogenesis in mouse muscle is independent of the vasodilator mechanism and quickly reversible." in: Acta physiologica (Oxford, England), Vol. 218, Issue 3, pp. 153-166, (2017) (PubMed).

    Dallabrida, Ismail, Pravda, Parodi, Dickie, Durand, Lai, Cassiola, Rogers, Rupnick: "Integrin binding angiopoietin-1 monomers reduce cardiac hypertrophy." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 22, Issue 8, pp. 3010-23, (2008) (PubMed).

    Câmpean, Karpe, Haas, Atalla, Peters, Rupprecht, Liebner, Acker, Plate, Amann: "Angiopoietin 1 and 2 gene and protein expression is differentially regulated in acute anti-Thy1.1 glomerulonephritis." in: American journal of physiology. Renal physiology, Vol. 294, Issue 5, pp. F1174-84, (2008) (PubMed).

  • 抗原
    Angiopoietin 1 (ANGPT1)
    别名
    Angiopoietin 1 (ANGPT1 产品)
    别名
    AGP1 antibody, AGPT antibody, ANG1 antibody, 1110046O21Rik antibody, Ang-1 antibody, Ang1 antibody, Agpt antibody, Agpt1 antibody, ang1 antibody, wu:fc76g06 antibody, ANG-1 antibody, angpt1 antibody, MGC80788 antibody, angiopoietin 1 antibody, angiopoietin 1 S homeolog antibody, ANGPT1 antibody, Angpt1 antibody, angpt1 antibody, angpt1.S antibody
    背景
    Anti Antiopoietin-1 Antibody recognizes Angiopoietin-1 (Ang-1) that has importance in the development of the endothelium by regulating tyrosine phosphorylation of the membrane receptor Tie-2/Tek. Ang-1 binding to Tie-2/Tek causes phosphorylation of the receptor. Ang-2 competes for this binding, and thus blocks receptor phosphorylation. Ang-1 has a potential fibrinogen-like domain at the carboxyl terminus and coiled-coil regions in the amino terminus. Ang-1 is prominently expressed in the myocardium of atrium and ventricle, mesenchymal and smooth muscle cells surrounding most blood vessels, and lung. In the adult, Ang-1 is also expressed in the heart and liver.
    Synonyms: AGP 1 antibody, AGP1 antibody, AGPT antibody, ANG 1 antibody, ANG1 antibody, Angiopoietin1 antibody, ANGPT 1 antibody, ANGPT1 antibody, KIAA0003 antibody
    基因ID
    11600, 46048213
    NCBI登录号
    NP_031452
    UniProt
    O08538
    途径
    RTK signaling, Glycosaminoglycan Metabolic Process
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