小鼠 anti-人 IgM (Fc Region) Antibody (APC)

ABIN94404 产品详细信息, 供应商: Log in to see
抗原
抗原表位
Fc Region
584
373
290
63
56
51
45
28
6
6
2
1
1
1
1
适用

1232
574
236
91
80
67
67
58
56
56
56
40
35
28
19
15
15
7
5
5
2
1
1
1
宿主
小鼠
1292
679
527
144
38
11
10
9
4
3
3
1
克隆类型 (克隆位点)
单克隆 ()
标记
APC
359
345
271
157
98
74
67
53
25
24
23
22
22
20
20
19
18
18
16
16
15
14
13
12
9
7
7
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
应用范围
Flow Cytometry (FACS)
选项
Supplier
Log in to see
Supplier Product No.
Log in to see
免疫原 Purified human IgM.
克隆位点 CH2
亚型 IgG1
特异性 The antibody CH2 reacts with Fc fragment of human IgM.
产品特性 The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography .
背景 Immunoglobulin M (IgM) is produced as a 900 kDa pentamer, which is an efficient complement binder. This antibody type is produced initially in the immune response and it is the first immunoglobulin class to be synthesized by a fetus or newborn. IgM antibodies do not cross the placenta. IgM concentration in blood is 0.12 g/l and its biological survival (plasma T1/2) is 5 days.
分子量 900 kDa
研究领域 Secondary Antibodies
应用备注 The reagent is designed for Flow Cytometry analysis. Suggested working concentration is 2 µg/mL. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Working concentrations should be determined by the investigator.
说明

Excitation/Emission wavelength: 650 nm/660 nm

限制 仅限研究用
状态 Liquid
浓度 0.1 mg/mL
缓冲液 The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
储存液 Sodium azide
注意事项 WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
注意事项 Do not freeze.
Avoid prolonged exposure to light.
储存条件 4 °C
储存方法 Store in the dark at 2-8 °C. Do not use after expiration date stamped on vial label. Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.
厂商提供的图像
Flow Cytometry (FACS) image for Mouse anti-Human IgM (Fc Region) antibody (APC) (ABIN94404) Surface staining of human peripheral blood cells with anti-human IgM (CH2) APC. Cells...
背景 Brinkmann, Heusser: "T cell-dependent differentiation of human B cells into IgM, IgG, IgA, or IgE plasma cells: high rate of antibody production by IgE plasma cells, but limited clonal expansion of IgE precursors." in: Cellular immunology, Vol. 152, Issue 2, pp. 323-32, 1994 (PubMed).

Balogh, Merétey, Falus, Bozsóky: "Serological abnormalities in juvenile chronic arthritis: a review of 46 cases." in: Annals of the rheumatic diseases, Vol. 39, Issue 2, pp. 129-34, 1980 (PubMed).

Franklin: "Structure and function of immunoglobulins." in: Acta endocrinologica. Supplementum, Vol. 194, pp. 77-95, 1975 (PubMed).

Fuller, Keyser: "Serum immunoglobulins after surgical operation." in: Clinical chemistry, Vol. 21, Issue 6, pp. 667-71, 1975 (PubMed).