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Cyclin D3 抗体 (AA 121-220) (Alexa Fluor 555)

CCND3 适用: 人, 兔 WB, IF (cc), IF (p), FACS 宿主: 兔 Polyclonal Alexa Fluor 555
产品编号 ABIN892929
发货至: 中国
  • 抗原 See all Cyclin D3 (CCND3) 抗体
    Cyclin D3 (CCND3)
    抗原表位
    • 33
    • 15
    • 7
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 121-220
    适用
    • 109
    • 45
    • 34
    • 15
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 兔
    宿主
    • 95
    • 16
    克隆类型
    • 86
    • 25
    多克隆
    标记
    • 52
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This Cyclin D3 antibody is conjugated to Alexa Fluor 555
    应用范围
    • 81
    • 34
    • 29
    • 26
    • 25
    • 19
    • 15
    • 15
    • 10
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)
    交叉反应
    人, 兔
    预测反应
    Mouse,Rat,Dog,Cow,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Cyclin D3
    亚型
    IgG
    Top Product
    Discover our top product CCND3 Primary Antibody
  • 应用备注
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • Souza, Silva, Calloway, Kucuk, Rossi, McLemore: "Genistein protects hematopoietic stem cells against G-CSF-induced DNA damage." in: Cancer prevention research (Philadelphia, Pa.), Vol. 7, Issue 5, pp. 534-44, (2014) (PubMed).

  • 抗原
    Cyclin D3 (CCND3)
    别名
    Cyclin D3 (CCND3 产品)
    别名
    zgc:103502 antibody, CCND3 antibody, 9230106B05Rik antibody, AA682053 antibody, AL024085 antibody, AW146355 antibody, C78795 antibody, cyclin D3 antibody, ccnd3 antibody, CCND3 antibody, Ccnd3 antibody
    背景

    Synonyms: G1/S-specific cyclin-D3, CCND3

    Background: Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.

    基因ID
    896
    UniProt
    P30281
    途径
    Cell Division Cycle, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
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