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Synaptophysin 2 抗体 (AA 257-261)

适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN871665
发货至: 中国
  • 抗原 See all Synaptophysin 2 products
    Synaptophysin 2
    抗原表位
    • 1
    • 1
    AA 257-261
    适用
    • 9
    • 7
    • 7
    大鼠
    宿主
    • 9
    克隆类型
    • 9
    多克隆
    标记
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Synaptophysin 2 antibody is un-conjugated
    应用范围
    Western Blotting (WB)
    特异性
    The antibody detects endogenous levels of total synaptophysin 2 protein.
    纯化方法
    Affinity purified
    免疫原
    Peptide sequence around AA 257-261 (G-P-T-S-F) derived from Rat synaptophysin 2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
  • 应用备注
    Western blotting: 1:500-1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原
    Synaptophysin 2
    Abstract
    Synaptophysin 2 产品
    别名
    synaptoporin antibody, Synpr antibody
    背景
    Synaptophysin (SYP) is a neuronal synaptic vesicle glycoprotein that is expressed in neuroendocrine cells and neoplasms, and thus can be used as a marker in tumor diagnosis (1). Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore (2). Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases (3). Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex
    分子量
    37 kDa
    基因ID
    66030
    NCBI登录号
    NP_076464
    UniProt
    P22831
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