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MAP2K4 抗体 (AA 352-356)

MAP2K4 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN871490
发货至: 中国
  • 抗原 See all MAP2K4 抗体
    MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))
    抗原表位
    • 34
    • 22
    • 18
    • 9
    • 9
    • 9
    • 8
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 352-356
    适用
    • 156
    • 75
    • 56
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 151
    • 10
    克隆类型
    • 148
    • 14
    多克隆
    标记
    • 89
    • 13
    • 11
    • 8
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAP2K4 antibody is un-conjugated
    应用范围
    • 89
    • 73
    • 60
    • 27
    • 23
    • 15
    • 15
    • 13
    • 8
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB)
    特异性
    The antibody detects endogenous levels of total MAP2K4 protein.
    纯化方法
    Affinity purified
    免疫原
    Peptide sequence around AA 352-356 (E-S-K-R-P) derived from Human MAP2K4. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    Top Product
    Discover our top product MAP2K4 Primary Antibody
  • 应用备注
    Western blotting: 1:500-1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原
    MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))
    别名
    MAP2K4 (MAP2K4 产品)
    别名
    JNKK antibody, JNKK1 antibody, MAPKK4 antibody, MEK4 antibody, MKK4 antibody, PRKMK4 antibody, SAPKK-1 antibody, SAPKK1 antibody, SEK1 antibody, SERK1 antibody, SKK1 antibody, Sek1 antibody, Serk1 antibody, MKK4A-l antibody, map2k4 antibody, zgc:136500 antibody, jnkk antibody, mek4 antibody, mkk4 antibody, sek1 antibody, jnkk1 antibody, serk1 antibody, xmek2 antibody, mapkk4 antibody, prkmk4 antibody, 142758_at antibody, CG9738 antibody, CT27508 antibody, D-MKK4 antibody, DMKK4 antibody, Dmel\\CG9738 antibody, JNKK2 antibody, Mpk4 antibody, SEK1/MKK4 antibody, dMKK4 antibody, dMkk4 antibody, hep antibody, ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 antibody, ATMEK4 antibody, ATMKK4 antibody, F19C24.26 antibody, F19C24_26 antibody, MAP KINASE KINASE 4 antibody, mitogen-activated protein kinase kinase 4 antibody, MKK4B antibody, zgc:194486 antibody, mitogen-activated protein kinase kinase 4 antibody, mitogen-activated protein kinase kinase 4a antibody, MAP kinase kinase 4 antibody, mitogen activated protein kinase kinase 4 antibody, mitogen-activated protein kinase kinase 4b antibody, MAP2K4 antibody, Map2k4 antibody, map2k4a antibody, map2k4 antibody, Mkk4 antibody, MKK4 antibody, map2k4b antibody
    背景
    SAPK/Erk kinase (SEK1), also known as MKK4 or Jun kinase kinase (JNKK), activates the MAP kinase homologues SAPK and JNK in response to various cellular stresses and inflamatory cytokines (1-3). Activation of SEK1 occurs through MEKK phosphorylation of serine and threonine residues at positions 257 and 261, respectively. Like MEK, SEK is a dual-specificity protein kinase that phosphorylates SAPK/JNK at a conserved T*PY* site in its activation loop (4). Phosphorylation by Akt at Ser80 inhibits SEK1 and suppresses stress-activated signal transduction
    分子量
    44 kDa
    基因ID
    6416
    NCBI登录号
    NP_003001
    UniProt
    P45985
    途径
    MAPK Pathway, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling
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