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- 抗原 See all NMDAR2A (GRIN2A) 抗体
- NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))
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抗原表位
- pTyr1325
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适用
- 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NMDAR2A antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Specific for the ~180k NMDAR NR2A-subunit protein phosphorylated at Tyr1325 in Western blots. Immunolabeling is completely blocked by blocked by the phosphopeptide used as the antigen but not by the corresponding dephosphopeptide.
- 交叉反应 （详细）
- Species reactivity (expected):Bovine and CanineSpecies reactivity (tested):Mouse and Rat.
- 纯化方法
- Affinity Chromatography.
- 免疫原
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Tyr1325 of NMDA NR2A.
- 亚型
- IgG
- Top Product
- Discover our top product GRIN2A Primary Antibody
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anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 851-950) antibody
GRIN2A 适用: 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 501-750) antibodyGRIN2A 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 1130-1400) antibodyGRIN2A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 23-165) antibodyGRIN2A 适用: 人 WB, IHC, ELISA, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 3G10F9 unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibodyGRIN2A 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S327-95 unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibodyGRIN2A 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S327A-38 unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibody (HRP)GRIN2A 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S327-95 HRP
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibody (HRP)GRIN2A 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S327A-38 HRP
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibody (FITC)GRIN2A 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S327-95 FITC
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibody (FITC)GRIN2A 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S327A-38 FITC
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody undiluted (in aliquots) at -20 °C.
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- 抗原
- NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))
- Abstract
- GRIN2A 产品
- 别名
- NMDAR2A antibody, nr2a antibody, GRIN2A antibody, EPND antibody, GluN2A antibody, NR2A antibody, glutamate ionotropic receptor NMDA type subunit 2A antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog antibody, glutamate receptor ionotropic, NMDA 2A antibody, glutamate receptor, ionotropic, NMDA2A (epsilon 1) antibody, GRIN2A antibody, grin2a.L antibody, LOC100438553 antibody, Grin2a antibody
- 背景
- The ion channels activated by glutamate that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death (Grosshans et al., 2002, Wenthold et al., 2003, Carroll and Zukin, 2002). The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS (Lovinger et al., 1989, Alvestad et al., 2003, Snell et al., 1996). Channels with physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits (Ishii et al., 1993). Recently, phosphorylation of Tyrosine 1325 of the NR2A subunit has been shown to be increased in human brain tissue sections from HIV-infected individuals with encephalitis (King et al., 2010). In addition, Tyr1325 phosphorylation has been linked with depression-related behavior (Taniguchi et al., 2009).Synonyms: GRIN2A, Glutamate [NMDA] Receptor subunit epsilon-1, NMDAR2A, NR2A
- 基因ID
- 24409
- NCBI登录号
- NP_036705
- 途径
- Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity
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