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GRM7 抗体 (pSer862)

GRM7 适用: 人, 大鼠, 小鼠, 犬, Cow, 斑马鱼, Non-Human Primate IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN784604
发货至: 中国
  • 抗原 See all GRM7 抗体
    GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
    抗原表位
    • 15
    • 8
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    pSer862
    适用
    • 51
    • 19
    • 15
    • 8
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠, 犬, Cow, 斑马鱼, Non-Human Primate
    宿主
    • 42
    • 11
    • 1
    克隆类型
    • 43
    • 11
    多克隆
    标记
    • 37
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GRM7 antibody is un-conjugated
    应用范围
    • 43
    • 24
    • 12
    • 10
    • 8
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Specific for the ~102k mGluR7 protein phosphorylated at Ser862. Immunolabeling is blocked by preadsorption of antibody with the phospho-peptide used as antigen but not by the corresponding dephosphopeptide.
    交叉反应 (详细)
    Species reactivity (expected):Bovine, Canine, Human, non-Human Primate and Zebrafish.
    Species reactivity (tested):Mouse and Rat.
    纯化方法
    Affinity Chromatography.
    免疫原
    Phosphopeptide corresponding to amino acid residues surrounding phospho-Ser862 of Rat mGluR7.
    亚型
    IgG
    Top Product
    Discover our top product GRM7 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
    注意事项
    Avoid repeated freezing and thawing.
  • 抗原
    GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
    别名
    mGluR7 / GRM7 (GRM7 产品)
    别名
    MGLUR7 antibody, GLUR7 antibody, GPRC1G antibody, MGLU7 antibody, 6330570A01Rik antibody, BB176677 antibody, C030018L03 antibody, E130018M02Rik antibody, Gpr1g antibody, Gprc1g antibody, mGluR7 antibody, glutamate metabotropic receptor 7 antibody, glutamate receptor, metabotropic 7 antibody, GRM7 antibody, Grm7 antibody
    背景
    Metabotropic glutamate receptors (mGluRs) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. They are implicated in many forms of neural plasticity as well as learning and memory and drug abuse (Bhattacharya et al., 2004, Francesconi et al., 2004, Wilson and Nicoll, 2001). The mGluRs are divided into three groups based on sequence identity and pharmacological properties: group I (mGluR1 and mGluR5) are localized in the perisynaptic region of the postsynaptic membrane, whereas group II (mGlur2 and mGluR3) and group III (mGluR4,6,7 and 8) are localized predominantly at presynaptic terminals. PKC phosphorylation of serine 862 on mGluR7 has been shown to be critical for stabilizing receptor surface expression and promoting binding to the synaptic PDZ-domain-containing protein PICK1 (Suh et al., 2008).Synonyms: GPRC1G, MGLUR7, Metabotropic glutamate receptor 7
    基因ID
    81672
    NCBI登录号
    NP_112302
    途径
    Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour
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