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NLRP5 抗体 (C-Term)

NLRP5 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN783707
发货至: 中国
  • 抗原 See all NLRP5 抗体
    NLRP5 (NLR Family, Pyrin Domain Containing 5 (NLRP5))
    抗原表位
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    • 12
    • 8
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 11
    • 1
    克隆类型
    • 12
    多克隆
    标记
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NLRP5 antibody is un-conjugated
    应用范围
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects NLRP5 at C-term.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    14 amino acid peptide near the carboxy terminus of human NALP5
    Top Product
    Discover our top product NLRP5 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原
    NLRP5 (NLR Family, Pyrin Domain Containing 5 (NLRP5))
    别名
    NLRP5 (NLRP5 产品)
    别名
    CLR19.8 antibody, MATER antibody, NALP5 antibody, PAN11 antibody, PYPAF8 antibody, Mater antibody, Nalp5 antibody, Op1 antibody, NLR family pyrin domain containing 5 antibody, NLR family, pyrin domain containing 5 antibody, NLRP5 antibody, Nlrp5 antibody
    背景
    NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP5, also known as MATER, is a maternal gene required for early embryonic development in mice. Increased NALP5 expression was observed in two neuronal injury models, and transient expression of recombinant NALP5 in neurons induced caspase-3 activation and apoptosis, suggesting that NALP5 also plays a role in caspase activation and apoptosis in injured neurons, and may thus represent a novel target for therapeutic treatment in neurodegenerative disorders.Synonyms: LRR and PYD domains-containing protein 5, MATER, NALP5
    基因ID
    126206
    NCBI登录号
    NP_703148
    UniProt
    P59047
    途径
    Inflammasome
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