NOD6, also known as NALP9, is a member of the NALP family, a group of proteins that typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD) and are involved in inflammation and innate immune defense. The bovine NOD6, which has 76 % homology to its human counterpart, has been suggested to be an oocyte marker gene. In adult tissues, NALP9 mRNA is expressed exclusively in ovary and testis.Synonyms: NACHT LRR and PYD domains-containing protein 9, NLRP9, Nucleotide-binding oligomerization domain protein 6, PAN12, PYRIN and NACHT-containing protein 12