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- 抗原 See all TYW1 抗体
- TYW1 (tRNA-YW Synthesizing Protein 1 Homolog (TYW1))
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抗原表位
- C-Term
- 适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TYW1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects TYW1 / RSAFD1 at C-term. TYW1 antibody is predicted to not cross-react with other TYW protein family members. At least three isoforms of TYW1 are known to exist, this antibody will only detect the two larger isoforms.
- 交叉反应 （详细）
- Species reactivity (tested):Human, rat
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 19 amino acid peptide near the carboxy terminus of human TYW1
- Top Product
- Discover our top product TYW1 Primary Antibody
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anti-tRNA-YW Synthesizing Protein 1 Homolog (TYW1) (AA 1-384) antibody
TYW1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-tRNA-YW Synthesizing Protein 1 Homolog (TYW1) (AA 1-384) antibodyTYW1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G5 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- 抗原
- TYW1 (tRNA-YW Synthesizing Protein 1 Homolog (TYW1))
- 别名
- TYW1 / RSAFD1 (TYW1 产品)
- 别名
- RSAFD1 antibody, TYW1A antibody, YPL207W antibody, RGD1310420 antibody, Rsafd1 antibody, AW125391 antibody, im:6898509 antibody, wu:fb74d01 antibody, zgc:153368 antibody, tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) antibody, S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase antibody, tRNA-yW synthesizing protein 1 homolog S homeolog antibody, tRNA-yW synthesizing protein 1 homolog antibody, TYW1 antibody, LOC100354908 antibody, tyw1.S antibody, Tyw1 antibody, tyw1 antibody
- 背景
- TYW1, also known as TYW1A, RSAFD1 or YPL207W, is a 732 amino acid protein containing one flavodoxin-like domain that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW1 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation. TYW1 binds to one 4Fe-4S cluster and is located on human chromosome 7. Defects in some of the genes on chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome, suggesting that TYW1 may play a role in these conditions.Synonyms: Radical S-adenosyl methionine and flavodoxin domain-containing protein 1, tRNA wybutosine-synthesizing protein 1 homolog, tRNA-yW-synthesizing protein
- 基因ID
- 55253
- NCBI登录号
- NP_060734
- UniProt
- Q9NV66
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