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- 抗原 See all ATP2C1 抗体
- ATP2C1 (ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1))
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抗原表位
- C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ATP2C1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects ATP2C1 (C-term). At least four isoforms of ATP2C1 are known to exist, this antibody will recognize only the three longest isoforms. ATP2C1 antibody will not cross-react with ATP2C2.
- 交叉反应 （详细）
- Species reactivity (tested):Human, mouse
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 19 amino acid peptide near the carboxy terminus of human ATP2C1
- Top Product
- Discover our top product ATP2C1 Primary Antibody
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anti-ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1) (AA 119-269) antibody
ATP2C1 适用: 人 ELISA, WB, IF, IP, RNAi 宿主: 小鼠 Monoclonal 2G1 unconjugated
anti-ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1) (AA 400-660) antibodyATP2C1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1) antibodyATP2C1 适用: 人, 猴 ELISA, WB, IHC 宿主: 小鼠 Monoclonal 4G12 unconjugated
anti-ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1) antibodyATP2C1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1) (AA 1-919) antibodyATP2C1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1) (AA 1-919) antibodyATP2C1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1) (AA 491-605) antibodyATP2C1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1) antibodyATP2C1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1) (C-Term) antibodyATP2C1 适用: 人, 小鼠, 大鼠, 猴, Cow, 犬, 豚鼠, 马, 兔, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1) (Internal Region) antibodyATP2C1 适用: 人, Cow WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- ATP2C1 (ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1))
- 别名
- ATP2C1 (ATP2C1 产品)
- 别名
- ATP2C1 antibody, ATP2C1A antibody, BCPM antibody, HHD antibody, PMR1 antibody, SPCA1 antibody, hSPCA1 antibody, Spca1 antibody, si:dkey-11p23.6 antibody, SPCA antibody, 1700121J11Rik antibody, AW061228 antibody, D930003G21Rik antibody, pmr1 antibody, ATPase secretory pathway Ca2+ transporting 1 antibody, ATPase, Ca++ transporting, type 2C, member 1 antibody, ATPase, Ca++-sequestering antibody, ATP2C1 antibody, atp2c1 antibody, Atp2c1 antibody
- 背景
- ATP2C1, also known as secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1, belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium from the cytosol to the Golgi lumen. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder characterized by persistent blisters and erosions of the skin. Unlike the related protein ATP2C2, ATP2C1 is ubiquitously expressed and displays a lower maximal turnover rate for overall Ca2+-ATPase reaction and a higher apparent affinity for cytosolic Ca2+ activation of phosphorylation. Recent evidence suggests that ATP2C1 is a key regulator of insulin-like growth factor receptor (IGF1R) processing in tumor progression in basal breast cancers.Synonyms: ATP-dependent Calcium pump PMR1, ATPase 2C1, Calcium-transporting ATPase type 2C member 1, HUSSY-28, KIAA1347, PMR1L
- 基因ID
- 27032
- NCBI登录号
- NP_001001485
- UniProt
- P98194
- 途径
- Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process
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