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LY75/DEC-205 抗体

LY75 适用: 人 WB, FACS, IHC (fro) 宿主: 小鼠 Monoclonal HD30 unconjugated
产品编号 ABIN781804
发货至: 中国
  • 抗原 See all LY75/DEC-205 (LY75) 抗体
    LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))
    适用
    • 42
    • 30
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    宿主
    • 40
    • 18
    • 6
    • 1
    • 1
    小鼠
    克隆类型
    • 33
    • 32
    • 1
    单克隆
    标记
    • 28
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    This LY75/DEC-205 antibody is un-conjugated
    应用范围
    • 23
    • 22
    • 20
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    • 14
    • 4
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    • 4
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody recognizes CD205, an approx. 200 kDa C-type lectin transmembrane protein of the MMR (macrophage mannose receptor) family, expressed at high levels on dendritic cells and thymic epithelial cells, and at low levels on lymphocytes, NK cells and monocytes.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Protein-A affinity chromatography
    纯度
    > 95 % pure (by SDS-PAGE)
    免疫原
    Recombinant Fc-tagged human CD205
    克隆位点
    HD30
    亚型
    IgG1
    Top Product
    Discover our top product LY75 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原
    LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))
    别名
    CD205 / DEC-205 (LY75 产品)
    别名
    LY75 antibody, MGC140308 antibody, DEC205 antibody, im:7150926 antibody, si:dkey-78p20.2 antibody, LYT75 antibody, CD205 antibody, DEC-205 antibody, CLEC13B antibody, GP200-MR6 antibody, LY-75 antibody, RGD1565962 antibody, Ly-75 antibody, lymphocyte antigen 75 antibody, CD205 protein antibody, CD302 antigen antibody, LY75 antibody, Cyan7822_2917 antibody, LY5 antibody, ly75 antibody, cd205 antibody, LOC100380704 antibody, LOC100433861 antibody, LOC100483541 antibody, Ly75 antibody
    背景
    CD205, also known as DEC-205, is an endocytic receptor of macrophage mannose receptor family. This 205 kDa C-type lectin transmembrane protein mediates adsorptive uptake and its intracellular domain contains coated pit localization sequence and distal acidic motif, which is required for recycling beyond early endosomes through deeper MHC II+ late endosomes and lysosomes. This unique pathway of receptor-mediated uptake proves to be necessary for presentation of antigenic peptides at low doses of ligand. CD205 is responsible for uptake and processing of captured antigens for dendritic cells.Synonyms: C-type lectin domain family 13 member B, CLEC13B, DEC205, LY75, Lymphocyte antigen 75, gp200-MR6
    基因ID
    100526664
    NCBI登录号
    NP_001185688
    UniProt
    O60449
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