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CD16 抗体

CD16 适用: 人 FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal c127 unconjugated
产品编号 ABIN781725
发货至: 中国
  • 抗原 See all CD16 抗体
    CD16
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD16 antibody is un-conjugated
    应用范围
    • 125
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    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    The antibody recognizes CD16, the low affinity receptor for IgG (FcγRIII). It detects both isoforms.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Affinity chromatography
    克隆位点
    C127
    亚型
    IgG1
    Top Product
    Discover our top product CD16 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    Reconstitute by adding 0.5 mL distilled water.
    缓冲液
    Stock solution contains 0.4 mg/mL IgG, phosphate buffered saline pH 7.2 (PBS), 5 mg/mL bovine serum albumin (BSA), and 0.09 % sodium azide as a preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Lyophilized product can be stored at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.
  • 抗原
    CD16
    别名
    CD16 (CD16 产品)
    别名
    Fcgr3 antibody, Fcgr3a antibody, CD16 antibody, FCGR3 antibody, FCGR3@ antibody, CD16b antibody, FCG3 antibody, FCR-10 antibody, FCRIII antibody, FCRIIIb antibody, FcRIII antibody, Fc fragment of IgG, low affinity IIa, receptor antibody, Fc fragment of IgG, low affinity IIIa, receptor (CD16a) antibody, Fc fragment of IgG receptor IIIb antibody, Fc fragment of IgG receptor IIIa antibody, Fc receptor, IgG, low affinity III antibody, Fc-gamma RIII antibody, Fcgr2a antibody, FCGR3A antibody, FCGR3B antibody, Fcgr3 antibody, FCGR3 antibody
    背景
    CD16 is expressed on the majority of NK cells, on granulocytes, monocytes and macrophages, and on a subset of T cells. CD16 is involved in antibody-dependent cellular cytotoxicity (ADCC). This molecule is encoded by FcγRIII-A or FcγRIII-B genes. The genetic heterogeneity of FcγRIII generates alternative membrane-anchored proteins with distinct signalling capacities when cross-linked by immune complexes. CD16 exists in two distinct forms, as a single-pass type I integral membrane protein (CD16a), and as a glycosyl phosphatidyl inositol (GPI) form (CD16b). In humans, the transmembrane form is expressed on NK cells and macrophages while the GPI linked form is expressed on granulocytes.Synonyms: CD16A, FCG3, FCGR3, FCGR3A, Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma RIIIa, FcR-10, FcRIII, FcRIIIa, IGFR3, IgG Fc receptor III-2, Low affinity immunoglobulin gamma Fc region receptor III-A
    基因ID
    2214
    NCBI登录号
    NP_000560
    UniProt
    P08637
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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