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MFSD2A 抗体 (AA 331-430) (Cy5)

MFSD2A 适用: 人, 小鼠, 大鼠 WB, FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal Cy5
产品编号 ABIN762030
发货至: 中国
  • 抗原 See all MFSD2A 抗体
    MFSD2A (Major Facilitator Superfamily Domain Containing 2A (MFSD2A))
    抗原表位
    • 15
    • 2
    • 2
    AA 331-430
    适用
    • 19
    • 18
    • 18
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 19
    克隆类型
    • 19
    多克隆
    标记
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MFSD2A antibody is conjugated to Cy5
    应用范围
    • 19
    • 13
    • 12
    • 12
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Cow,Pig,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human MFSD2A
    亚型
    IgG
  • 应用备注
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    MFSD2A (Major Facilitator Superfamily Domain Containing 2A (MFSD2A))
    别名
    MFSD2A (MFSD2A 产品)
    别名
    1700018O18Rik antibody, Mfsd2 antibody, RGD1310174 antibody, MFSD2 antibody, NLS1-A antibody, Sodium-dependent LPC symporter 1-A antibody, mfsd2a antibody, zgc:101615 antibody, mfsd2 antibody, NLS1-B antibody, Sodium-dependent LPC symporter 1-B antibody, mfsd2b antibody, zgc:101069 antibody, major facilitator superfamily domain containing 2A antibody, major facilitator superfamily domain containing 2aa antibody, major facilitator superfamily domain containing 2A L homeolog antibody, major facilitator superfamily domain containing 2ab antibody, MFSD2A antibody, mfsd2a antibody, Mfsd2a antibody, mfsd2aa antibody, mfsd2a.L antibody, mfsd2ab antibody
    背景

    Synonyms: NLS1, MFSD2, Sodium-dependent lysophosphatidylcholine symporter 1, Sodium-dependent LPC symporter 1, Major facilitator superfamily domain-containing protein 2A, MFSD2A, HMFN0656, PP9177, UNQ300/PRO341

    Background: Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons. Does not transport docosahexaenoic acid in unesterified fatty acid. Specifically required for blood-brain barrier formation and function, probably by mediating lipid transport. Not required for central nervous system vascular morphogenesis (By similarity). Acts as a transporter for tunicamycin, an inhibitor of asparagine-linked glycosylation. In placenta, acts as a receptor for ERVFRD-1/syncytin-2 and is required for trophoblast fusion (PubMed:18988732).

    基因ID
    84879
    UniProt
    Q8NA29
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