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ADAMTSL2 抗体 (AA 522-580) (FITC)

ADAMTSL2 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal FITC
产品编号 ABIN758988
发货至: 中国
  • 抗原 See all ADAMTSL2 抗体
    ADAMTSL2 (ADAMTS-Like 2 (ADAMTSL2))
    抗原表位
    • 14
    • 1
    • 1
    • 1
    • 1
    AA 522-580
    适用
    • 21
    • 3
    • 1
    • 1
    • 1
    宿主
    • 20
    • 1
    克隆类型
    • 21
    多克隆
    标记
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This ADAMTSL2 antibody is conjugated to FITC
    应用范围
    • 19
    • 12
    • 12
    • 7
    • 5
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    预测反应
    Mouse,Rat
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human ADAMTSL2
    亚型
    IgG
    Top Product
    Discover our top product ADAMTSL2 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    ADAMTSL2 (ADAMTS-Like 2 (ADAMTSL2))
    别名
    ADAMTSL2 (ADAMTSL2 产品)
    别名
    ADAMTSL2 antibody, GPHYSD1 antibody, A930008K15Rik antibody, tcp-1 antibody, RGD1305459 antibody, ADAMTS-like 2 antibody, ADAMTS like 2 antibody, ADAMTS-like protein 2 antibody, ADAMTSL2 antibody, adamtsl2 antibody, LOC100589493 antibody, Adamtsl2 antibody
    背景

    Synonyms: ADAMTS like 2, ADAMTS like protein 2, ADAMTS-like protein 2, ADAMTSL 2, ADAMTSL-2, ADAMTSL2, ATL2_HUMAN.

    Background: ADAMTS (A Disintegrin And Metalloproteinase Domain with Thrombospondin type 1 Modules) is a family of zinc-dependent proteases that are implicated in a variety of normal and pathological conditions, including arthritis and cancer. ADAMTS protein family members contain an amino-terminal propeptide domain, a metalloproteinase domain, a disintegrin-like domain and a carboxy-terminus that contains a varying number of Thrombospondin type 1 (TSP-1) motifs. ADAMTS-L2 (ADAMTS-like protein 2) is a 951 amino acid secreted protein that is highly expressed in lung, kidney and liver. Mutations in the gene encoding ADAMTS are the cause of geleophysic dysplasia, an autosomal recessive disorder characterized by cardiac vavular anomalies, short stature, thick skin and brachydactyly. In individuals affected with geleophysic dysplasia, there is a significant increase in total active TGF-beta 1 and nuclear locations of p-SAMD2 in fibroblasts. Interestingly, ADAMTS-L2 interacts with LTBP-1, a glycoprotein that is part of the platelet-derived TGF-beta 1 complex.

    基因ID
    9719
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