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LAG3 抗体 (AA 210-260) (PE)

LAG3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal PE
产品编号 ABIN748518
发货至: 中国
  • 抗原 See all LAG3 抗体
    LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
    抗原表位
    • 15
    • 14
    • 9
    • 7
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 210-260
    适用
    • 87
    • 33
    • 9
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 51
    • 35
    • 7
    • 4
    克隆类型
    • 52
    • 42
    • 1
    多克隆
    标记
    • 52
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LAG3 antibody is conjugated to PE
    应用范围
    • 68
    • 36
    • 30
    • 29
    • 25
    • 22
    • 15
    • 13
    • 13
    • 10
    • 10
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    人, 小鼠
    预测反应
    Rat,Cow,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Lymphocyte Activation Gene 3
    亚型
    IgG
    Top Product
    Discover our top product LAG3 Primary Antibody
  • 应用备注
    FCM(1:20-100)
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • Parodi, Battaglia, Kalli, Ferrera, Conteduca, Tardito, Stringara, Ivaldi, Negrini, Borgonovo, Simonato, Traverso, Carmignani, Fenoglio, Filaci: "CD39 is highly involved in mediating the suppression activity of tumor-infiltrating CD8+ T regulatory lymphocytes." in: Cancer immunology, immunotherapy : CII, Vol. 62, Issue 5, pp. 851-62, (2013) (PubMed).

  • 抗原
    LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
    别名
    Lymphocyte Activation Gene 3 (LAG3 产品)
    别名
    CD223 antibody, LAG-3 antibody, Ly66 antibody, lymphocyte activating 3 antibody, lymphocyte-activation gene 3 antibody, LAG3 antibody, Lag3 antibody
    背景

    Synonyms: CD223, Lymphocyte activation gene 3 protein, LAG-3, Lag3

    Background: Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.

    基因ID
    297596
    UniProt
    Q5BK54
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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