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Id2 抗体 (AA 31-134) (Biotin)

Id2 适用: 大鼠 ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN747475
发货至: 中国
  • 抗原 See all Id2 抗体
    Id2 (Inhibitor of DNA Binding 2 (Id2))
    抗原表位
    • 14
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-134
    适用
    • 31
    • 30
    • 14
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    大鼠
    宿主
    • 40
    • 5
    • 1
    克隆类型
    • 42
    • 4
    多克隆
    标记
    • 20
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Id2 antibody is conjugated to Biotin
    应用范围
    • 20
    • 17
    • 13
    • 13
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Due to the similarity of this protein with ID1, this antibody has a chance to have light cross-reactivity with ID1 due to a 77 % sequence similarity in the range of our immunogen.
    交叉反应
    大鼠
    预测反应
    Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human GIG8/ID2
    亚型
    IgG
    Top Product
    Discover our top product Id2 Primary Antibody
  • 应用备注
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    Id2 (Inhibitor of DNA Binding 2 (Id2))
    别名
    ID2 (Id2 产品)
    别名
    AI255428 antibody, C78922 antibody, Idb2 antibody, bHLHb26 antibody, Ac2-300 antibody, GIG8 antibody, ID2A antibody, ID2H antibody, XId2 antibody, id2-A antibody, inhibitor of DNA binding 2 antibody, inhibitor of DNA binding 2, HLH protein antibody, inhibitor of DNA binding 2 L homeolog antibody, Id2 antibody, ID2 antibody, id2.L antibody
    背景

    Synonyms: GIG8, ID2A, ID2H, bHLHb26, DNA-binding protein inhibitor ID-2, Class B basic helix-loop-helix protein 26, Inhibitor of DNA binding 2, Inhibitor of differentiation 2, ID2

    Background: Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism.

    基因ID
    3398
    UniProt
    Q02363
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