TNFRSF10B 抗体 (AA 301-381)
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- 抗原 See all TNFRSF10B 抗体
- TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
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抗原表位
- AA 301-381
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TNFRSF10B antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from mouse DR5
- 亚型
- IgG
- Top Product
- Discover our top product TNFRSF10B Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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Dihydroartemisinin enhances Apo2L/TRAIL-mediated apoptosis in pancreatic cancer cells via ROS-mediated up-regulation of death receptor 5." in: PLoS ONE, Vol. 7, Issue 5, pp. e37222, (2012) (PubMed).
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Dihydroartemisinin enhances Apo2L/TRAIL-mediated apoptosis in pancreatic cancer cells via ROS-mediated up-regulation of death receptor 5." in: PLoS ONE, Vol. 7, Issue 5, pp. e37222, (2012) (PubMed).
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- 抗原
- TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
- 别名
- TRAILR2/DR5/CD262 (TNFRSF10B 产品)
- 别名
- TNFRSF10B antibody, dr5 antibody, cd262 antibody, killer antibody, trick2 antibody, trickb antibody, xDR-M1 antibody, xDR-M2 antibody, ztnfr9 antibody, trailr2 antibody, trick2a antibody, trick2b antibody, CD262 antibody, DR5 antibody, KILLER antibody, KILLER/DR5 antibody, TRAIL-R2 antibody, TRAILR2 antibody, TRICK2 antibody, TRICK2A antibody, TRICK2B antibody, TRICKB antibody, ZTNFR9 antibody, Ly98 antibody, MK antibody, tumor necrosis factor receptor superfamily, member 10b antibody, tumor necrosis factor receptor superfamily member 10b S homeolog antibody, tumor necrosis factor receptor superfamily member 10b L homeolog antibody, tumor necrosis factor receptor superfamily member 10b antibody, TNF receptor superfamily member 10b antibody, Tnfrsf10b antibody, TNFRSF10B antibody, tnfrsf10b.S antibody, tnfrsf10b.L antibody, tnfrsf10b antibody
- 背景
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Synonyms: MK, DR5, Ly98, KILLER, TRICKB, TRAILR2, TRICK2A, TRICK2B, Tumor necrosis factor receptor superfamily member 10B, Death receptor 5, CD262, Tnfrsf10b
Background: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis (By similarity).
- 基因ID
- 21933
- UniProt
- Q9QZM4
- 途径
- p53 Pathway, Apoptosis, Positive Regulation of Endopeptidase Activity
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