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ADAM17 抗体 (AA 201-300)

Name: ADAM17 抗体 (AA 201-300)
SKU: ABIN705671
Availability: OutOfStock

ADAM17 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded human placenta labeled with Anti-ADAM17/CD156b Polyclonal Antibody, Unconjugated (ABIN705671) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

IHC

Mouse thymocytes probed with Rabbit Anti-ADAM17 Polyclonal Antibody, Unconjugated .

FACS

U937 cells probed with ADAM17 Polyclonal Antibody, Unconjugated at 1:100 for 30 minutes followed by incubation with a PE conjugated secondary (green) for 30 minutes compared to control cells (blue), secondary only (light blue) and isotype control (orange).

FACS

Paraformaldehyde-fixed, paraffin embedded rat kidney, Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with ADAM17 Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C, followed by a conjugated secondary and DAB staining.

IHC (p)

4 images

(1 reference)

产品编号 ABIN705671

发货至: 中国

Datasheet as PDF

抗原 See all ADAM17 抗体

ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
抗原表位
15

13

8

8

8

7

6

5

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 201-300
适用
109

53

51

4

4

4

1

1
人, 大鼠, 小鼠
宿主
94

13

2

1

1
兔
Compatible Secondaries
克隆类型
86

25
多克隆
标记
53

10

7

5

4

4

3

3

3

3

3

3

1

1

1

1

1

1

1

1

1

1
This ADAM17 antibody is un-conjugated
应用范围
81

47

39

14

14

13

12

10

10

6

5

3

3

2

2
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人, 小鼠, 大鼠

预测反应

Dog,Cow,Pig,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human ADAM17

亚型

IgG

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anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 215-314) antibody
ADAM17 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 1F6 unconjugated

anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 226-473) antibody
ADAM17 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-ADAM Metallopeptidase Domain 17 (ADAM17) (C-Term) antibody
Verified ADAM17 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-ADAM Metallopeptidase Domain 17 (ADAM17) (C-Term) antibody
KO Validated ADAM17 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-ADAM Metallopeptidase Domain 17 (ADAM17) antibody
ADAM17 适用: 人, 大鼠, 小鼠 WB, FACS, IF (cc) 宿主: 兔 Monoclonal 9E7 unconjugated

anti-ADAM Metallopeptidase Domain 17 (ADAM17) (pThr735) antibody
ADAM17 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-ADAM Metallopeptidase Domain 17 (ADAM17) (N-Term) antibody
ADAM17 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated

anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 215-315) antibody
ADAM17 适用: 人 WB, ELISA, IHC, IHC (p), PLA 宿主: 小鼠 Monoclonal 1F6 unconjugated

anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 215-315) antibody
ADAM17 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 1F6 unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Li, Xie, He, Wang, Duan, Yang, Wang: "Identification of ADAM10 and ADAM17 with potential roles in the spermatogenesis of the Chinese mitten crab, Eriocheir sinensis." in: Gene, Vol. 562, Issue 1, pp. 117-27, (2015) (PubMed).
抗原

ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

别名

ADAM17 (ADAM17 产品)

别名

ADAM18 antibody, CD156B antibody, CSVP antibody, NISBD antibody, TACE antibody, CD156b antibody, Tace antibody, adam17 antibody, si:dkey-81b15.2 antibody, adam18 antibody, cd156b antibody, csvp antibody, tace antibody, fc20b01 antibody, wu:fc20b01 antibody, zgc:63886 antibody, ADAM metallopeptidase domain 17 antibody, a disintegrin and metallopeptidase domain 17 antibody, ADAM metallopeptidase domain 17b antibody, ADAM metallopeptidase domain 17 L homeolog antibody, ADAM metallopeptidase domain 17a antibody, ADAM17 antibody, Adam17 antibody, adam17b antibody, adam17.L antibody, adam17a antibody

背景

Synonyms: CSVP, TACE, NISBD, ADAM18, CD156B, NISBD1, Disintegrin and metalloproteinase domain-containing protein 17, ADAM 17, Snake venom-like protease, TNF-alpha convertase, TNF-alpha-converting enzyme, ADAM17
Background: Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). Plays a role in the proteolytic processing of ACE2.

基因ID

6868

UniProt

P78536

途径

Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus