我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

YAP1 抗体 (AA 131-330)

Name: YAP1 抗体 (AA 131-330)
SKU: ABIN701485
Availability: OutOfStock

YAP1 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

L1 mouse liver lysates L2 mouse lung lysates probed with Anti-YAP1 Polyclonal Antibody, Unconjugated at 1:5000 for 90 min at 37˚C.

Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti-YAP1 Polyclonal Antibody, Unconjugated (ABIN701485) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

IHC

Formalin-fixed and paraffin embedded human breast carcinoma labeled with Rabbit Anti-YAP1 Polyclonal Antibody, Unconjugated 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC (p)

Formalin-fixed and paraffin embedded human colon carcinoma labeled with Rabbit Anti-YAP1 Polyclonal Antibody, Unconjugated 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC (p)

4 images

(1 reference)

产品编号 ABIN701485

发货至: 中国

Datasheet as PDF

抗原 See all YAP1 抗体

YAP1 (Yes-Associated Protein 1 (YAP1))
抗原表位
25

15

14

13

10

7

7

6

6

6

5

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 131-330
适用
148

81

61

6

5

5

4

3

3

3

2

2

2

1
人, 小鼠
宿主
130

17

1

1
兔
Compatible Secondaries
克隆类型
119

29

1
多克隆
标记
79

9

7

6

5

5

5

5

5

5

4

4

2

2

2

2

2
This YAP1 antibody is un-conjugated
应用范围
108

52

31

27

26

26

23

18

12

9

7

6

3

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人, 小鼠

预测反应

Rat,Dog,Cow,Pig,Horse,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human YAP1

亚型

IgG

Top Product

Discover our top product YAP1 Primary Antibody
anti-Yes-Associated Protein 1 (YAP1) (AA 53-161) antibody
YAP1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2F12 unconjugated

anti-Yes-Associated Protein 1 (YAP1) antibody
YAP1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Yes-Associated Protein 1 (YAP1) antibody
YAP1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1A12 unconjugated

anti-Yes-Associated Protein 1 (YAP1) antibody
KO Validated YAP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Yes-Associated Protein 1 (YAP1) antibody
YAP1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated

anti-Yes-Associated Protein 1 (YAP1) (C-Term) antibody
YAP1 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, 绵羊, 马, Pig, Cow, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Yes-Associated Protein 1 (YAP1) (AA 53-162) antibody
YAP1 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 2F12 unconjugated

anti-Yes-Associated Protein 1 (YAP1) antibody
YAP1 适用: 人 WB, IHC (p), FACS, EIA 宿主: 小鼠 Monoclonal 1A12 unconjugated

anti-Yes-Associated Protein 1 (YAP1) antibody
YAP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Yes-Associated Protein 1 (YAP1) (pSer127) antibody
YAP1 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Li, Shang, Shu, Zhang, Ji, Sun, Li, Xie: "gga-miR-375 plays a key role in tumorigenesis post subgroup J avian leukosis virus infection." in: PLoS ONE, Vol. 9, Issue 4, pp. e90878, (2014) (PubMed).
抗原

YAP1 (Yes-Associated Protein 1 (YAP1))

别名

YAP1 (YAP1 产品)

别名

YAP antibody, YAP2 antibody, YAP65 antibody, YKI antibody, xyap antibody, yap antibody, yap2 antibody, yap65 antibody, yki antibody, AI325207 antibody, Yap antibody, Yap65 antibody, Yki antibody, Yorkie antibody, cb194 antibody, sb:cb194 antibody, si:ch211-181p1.5 antibody, si:dkey-3b8.3 antibody, wu:fc18c04 antibody, zgc:158380 antibody, Yes associated protein 1 antibody, Yes associated protein 1 S homeolog antibody, yes-associated protein 1 antibody, Yes-associated protein 1 antibody, YAP1 antibody, yap1.S antibody, Yap1 antibody, yap1 antibody

背景

Synonyms: YAP, YKI, COB1, YAP2, YAP65, Transcriptional coactivator YAP1, Yes-associated protein 1, Protein yorkie homolog, Yes-associated protein YAP65 homolog, YAP1
Background: Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Plays a key role to control cell proliferation in response to cell contact. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. The presence of TEAD transcription factors are required for it to stimulate gene expression, cell growth, anchorage-independent growth, and epithelial mesenchymal transition (EMT) induction. Isoform 2 and isoform 3 can activate the C-terminal fragment (CTF) of ERBB4 (isoform 3).

基因ID

10413

UniProt

P46937

途径

MAPK Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha