Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (AA 160-200), (pThr183), (pTyr185) 抗体

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抗原
  • erk1/2
  • mitogen-activated protein kinase
  • erk1/2
抗原表位
pThr183, pTyr185, AA 160-200
115
104
30
29
28
19
18
17
15
15
15
15
14
11
9
9
9
8
7
7
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
适用
人, 小鼠, 大鼠, 牛
403
312
300
56
24
15
9
8
8
8
7
6
5
5
3
3
2
2
2
1
1
1
1
宿主

331
76
6
克隆类型
多克隆
标记
非结合性
12
11
11
9
7
7
7
6
6
6
6
6
6
6
2
2
2
1
1
1
1
1
1
应用范围
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
291
106
81
77
60
54
39
38
14
10
6
4
3
2
2
2
2
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免疫原 KLH conjugated synthetic phosphopeptide derived from mouse ERK2 around the phosphorylation site of Thr183 and Tyr 185
亚型 IgG
纯化方法 Purified by Protein A.
别名 ERK1, ERK2 (MAPK1/3 Antibody 摘要)
Sub Type Cocktail
背景

Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity (By similarity).

Subcellular location: Cytoplasm

Synonyms: ERK, Erk2, MAPK2, PRKM2, Prkm1, C78273, p41mapk, p42mapk, AA47128, AU18647, 93612K14Rik, Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2, Mapk1, Mapk

基因ID 26413
UniProt P63085
应用备注 WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
限制 仅限研究用
状态 Liquid
浓度 1 μg/μL
缓冲液 Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
储存条件 -20 °C
储存方法 Store at -20°C
有效期 12 months
厂商提供的图像
Immunohistochemistry (IHC) image for anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (AA 160-200), (pThr183), (pTyr185) 抗体 (ABIN687727) Formalin-fixed and paraffin embedded mouse embryo tissue labeled with Rabbit Anti-ERK...
SDS-PAGE (SDS) image for anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (AA 160-200), (pThr183), (pTyr185) 抗体 (ABIN687727) L1 rat liver lysates L2 rat kidney lysates probed with Rabbit Anti-ERK1 (Thr203/Tyr20...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (AA 160-200), (pThr183), (pTyr185) 抗体 (ABIN687727) Formalin-fixed and paraffin embedded mouse embryo tissue labeled with Rabbit Anti-ERK...
有引用在: Cong, Chen: "Neuroprotective Effect of Ginsenoside Rd in Spinal Cord Injury Rats." in: Basic & clinical pharmacology & toxicology, Vol. 119, Issue 2, pp. 193-201, 2016 (PubMed).

Yu, Shi, Qi, Zhao, Gao, Li: "Gypenoside Protects Cardiomyocytes against Ischemia-Reperfusion Injury via the Inhibition of Mitogen-Activated Protein Kinase Mediated Nuclear Factor Kappa B Pathway In Vitro and In Vivo." in: Frontiers in pharmacology, Vol. 7, pp. 148, 2016 (PubMed). Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)).

Zhao, Xue, Guo, Sun, Liu, Wang: "Inhibition of endocan attenuates monocrotaline-induced connective tissue disease related pulmonary arterial hypertension." in: International immunopharmacology, Vol. 42, pp. 115-121, 2016 (PubMed). Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)).

Zhao, Liu, Liu, Han, Zhao: "Betulin attenuates lung and liver injuries in sepsis." in: International immunopharmacology, Vol. 30, pp. 50-6, 2015 (PubMed).

Rosenzweig, Djap, Ou, Quinn: "Mechanical injury of bovine cartilage explants induces depth-dependent, transient changes in MAP kinase activity associated with apoptosis." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 20, Issue 12, pp. 1591-602, 2012 (PubMed).