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MFN2 抗体 (AA 1-120)

Name: MFN2 抗体 (AA 1-120)
SKU: ABIN682528
Availability: OutOfStock

MFN2 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded human kidney labeled with Rabbit Anti Mitofusin 2/MFN2 Polyclonal Antibody, Unconjugated (ABIN682528) at 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC

Formalin-fixed and paraffin embedded human kidney labeled with Rabbit Anti Mitofusin 2/MFN2 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC (p)

Formalin-fixed and paraffin embedded mouse kidney labeled with Rabbit Anti Mitofusin 2/MFN2 Polyclonal Antibody, Unconjugated (ABIN682528) at 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC

Formalin-fixed and paraffin embedded human breast cancer tissue labeled with Anti-Mitofusin 2 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining.

IHC (p)

Formalin-fixed and paraffin embedded human kidney labeled with Rabbit Anti-Mitofusin 2 Polyclonal Antibody, Unconjugated used at 1:200 dilution for 40 minutes at 37°C.

IF (p)

5 images

(2 references)

产品编号 ABIN682528

发货至: 中国

Datasheet as PDF

抗原 See all MFN2 抗体

MFN2 (Mitofusin 2 (MFN2))
抗原表位
29

15

7

6

5

3

2

2

2

2

1

1

1

1

1

1

1
AA 1-120
适用
79

51

35

19

4

4

4

4

3

2

2

2

2

1

1

1

1
人, 小鼠, 大鼠, 兔
宿主
66

32

2
兔
Compatible Secondaries
克隆类型
67

33
多克隆
标记
35

8

7

7

6

4

4

4

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1
This MFN2 antibody is un-conjugated
应用范围
89

51

33

23

22

15

15

12

12

8

2

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人, 小鼠, 兔, 大鼠

预测反应

Dog,Cow,Pig,Horse,Chicken

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human Mitofusin 2

亚型

IgG

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anti-Mitofusin 2 (MFN2) (AA 661-757) antibody
MFN2 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 4H8 unconjugated

anti-Mitofusin 2 (MFN2) (AA 500-600) antibody
MFN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (AA 687-757) antibody
MFN2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (AA 447-476) antibody
MFN2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody
MFN2 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S153-5 unconjugated

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (HRP)
MFN2 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S153-5 HRP

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (FITC)
MFN2 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S153-5 FITC

anti-Mitofusin 2 (MFN2) (N-Term) antibody
MFN2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (Alkaline Phosphatase (AP))
MFN2 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S153-5 Alkaline Phosphatase (AP)

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (Biotin)
MFN2 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S153-5 Biotin

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Hui, Lu, Han, Zhou, Liu, Li, Jin: "Resveratrol improves mitochondrial function in the remnant kidney from 5/6 nephrectomized rats." in: Acta histochemica, Vol. 119, Issue 4, pp. 392-399, (2017) (PubMed).

Ku, Ji, Zhang, Li, Sang: "PM2.5, SO2 and NO2 co-exposure impairs neurobehavior and induces mitochondrial injuries in the mouse brain." in: Chemosphere, Vol. 163, pp. 27-34, (2016) (PubMed).
抗原

MFN2 (Mitofusin 2 (MFN2))

别名

Mitofusin 2 (MFN2 产品)

别名

CG3869 antibody, Dmel\\CG3869 antibody, MARF antibody, Marf-1 antibody, Mfn antibody, anon-WO0125274.3 antibody, dMFN antibody, dMfn antibody, dmfn antibody, marf antibody, mfn antibody, mfn2 antibody, MFN2 antibody, hsg antibody, cmt2a antibody, cprp1 antibody, cmt2a2 antibody, CMT2A antibody, CMT2A2 antibody, CPRP1 antibody, HSG antibody, D630023P19Rik antibody, Fzo antibody, mg:cb01g09 antibody, si:dkeyp-104h9.2 antibody, wu:fb79a11 antibody, mitofusin 2 antibody, Mitochondrial assembly regulatory factor antibody, mitofusin-2 antibody, mitofusin 2 L homeolog antibody, MFN2 antibody, Marf antibody, mfn2 antibody, LOC100186475 antibody, Mfn2 antibody, mfn2.L antibody

背景

Synonyms: HSG, MARF, CMT2A, CPRP1, CMT2A2, Mitofusin-2, Transmembrane GTPase MFN2, MFN2, KIAA0214
Background: Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Is required for PARK2 recruitment to dysfunctional mitochondria. Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress. Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions.

基因ID

9927

UniProt

O95140

途径

Skeletal Muscle Fiber Development