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SCNN1A 抗体 (AA 201-300)

SCNN1A 适用: 大鼠, 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN682243
发货至: 中国
  • 抗原 See all SCNN1A 抗体
    SCNN1A (Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A))
    抗原表位
    • 63
    • 22
    • 21
    • 11
    • 10
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300
    适用
    • 99
    • 44
    • 38
    • 20
    • 10
    大鼠, 人, 小鼠
    宿主
    • 82
    • 43
    克隆类型
    • 82
    • 43
    多克隆
    标记
    • 27
    • 11
    • 10
    • 10
    • 10
    • 10
    • 9
    • 9
    • 9
    • 9
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SCNN1A antibody is un-conjugated
    应用范围
    • 115
    • 104
    • 37
    • 36
    • 34
    • 21
    • 9
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Cow,Sheep,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Alpha-ENaC
    亚型
    IgG
    Top Product
    Discover our top product SCNN1A Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Scortegagna, Berthon, Settas, Giannakou, Garcia, Li, James, Liddington, Vilches-Moure, Stratakis, Ronai: "The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion." in: JCI insight, Vol. 2, Issue 23, (2019) (PubMed).

    Yamamoto, Hotta, Maeda, Kataoka, Maeda, Hamakawa, Sasaki, Yasui, Asai, Kimura: "Mineralocorticoid receptor stimulation induces urinary storage dysfunction via upregulation of epithelial sodium channel expression in the rat urinary bladder epithelium." in: Journal of pharmacological sciences, Vol. 130, Issue 4, pp. 219-25, (2016) (PubMed).

  • 抗原
    SCNN1A (Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A))
    别名
    Alpha-ENaC (SCNN1A 产品)
    背景

    Synonyms: BESC2, ENaCa, SCNEA, SCNN1, ENaCalpha, Amiloride-sensitive sodium channel subunit alpha, Alpha-NaCH, Epithelial Na(+) channel subunit alpha, Alpha-ENaC, Nonvoltage-gated sodium channel 1 subunit alpha, SCNN1A

    Background: Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.

    基因ID
    6337
    UniProt
    P37088
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