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PRKAA2 抗体
PRKAA2
适用: 人
WB, IF
宿主: 小鼠
Monoclonal
206CT5-4-2
unconjugated
PRKAA2抗体详情
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抗原
See all PRKAA2 抗体
PRKAA2
(Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
适用
All reactivities for PRKAA2 抗体
人
宿主
All hosts for PRKAA2 抗体
小鼠
克隆类型
All clonalities for PRKAA2 抗体
单克隆
标记
All conjugates for PRKAA2 抗体
This PRKAA2 antibody is un-conjugated
应用范围
All applications for PRKAA2 抗体
Western Blotting (WB), Immunofluorescence (IF)
纯化方法
This antibody is purified through a protein G column, followed by dialysis against PBS.
免疫原
This PRKAA2 monoclonal antibody is generated from mouse immunized with PRKAA2 recombinant protein.
克隆位点
206CT5-4-2
亚型
IgG2a kappa
Top Product
Discover our top product PRKAA2 Primary Antibody
Alternatives
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anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 351-450) antibody
PRKAA2
适用: 人, 小鼠, 大鼠
WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
IF: 1:10~50. WB: 1:1000
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期
6 months
PRKAA2目标详情
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抗原
PRKAA2
(Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
别名
PRKAA2 (PRKAA2 产品 )
别名
AMPK antibody, AMPK2 antibody, AMPKa2 antibody, PRKAA antibody, Ampk antibody, Ampka2 antibody, 2310008I11Rik antibody, A830082D05 antibody, AMPKalpha2 antibody, AMPKA2 antibody, ampk antibody, ampk2 antibody, prkaa antibody, prkaa1 antibody, PRKAA2 antibody, protein kinase AMP-activated catalytic subunit alpha 2 antibody, protein kinase, AMP-activated, alpha 2 catalytic subunit antibody, protein kinase, AMP-activated, alpha 2 catalytic subunit S homeolog antibody, PRKAA2 antibody, Prkaa2 antibody, prkaa2.S antibody, prkaa2 antibody
背景
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
分子量
62320
基因ID
5563
NCBI登录号
NP_006243
UniProt
P54646
途径
AMPK Signaling , Carbohydrate Homeostasis , Chromatin Binding , Regulation of Carbohydrate Metabolic Process , Warburg Effect
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