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VAV1 抗体 (AA 437-466)

Name: VAV1 抗体 (AA 437-466)
SKU: ABIN657774
Availability: OutOfStock

VAV1 适用: 人 WB 宿主: 兔 Polyclonal RB33825 unconjugated

VAV1 Antibody (Center) (ABIN657774 and ABIN2846749) western blot analysis in CEM cell line lysates (35 μg/lane).

1 image

产品编号 ABIN657774

发货至: 中国

Datasheet as PDF

抗原 See all VAV1 抗体

VAV1 (Vav 1 Oncogene (VAV1))
抗原表位
15

11

10

7

6

6

6

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 437-466
适用
69

39

25

2

2

1

1

1

1

1

1
人
宿主
67

4
兔
Compatible Secondaries
克隆类型
67

4
多克隆
标记
40

5

3

3

3

3

3

3

2

2

2

2
This VAV1 antibody is un-conjugated
应用范围
46

34

12

7

6

5

4

2

1

1

1

1
Western Blotting (WB)

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This VAV1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 437-466 amino acids from the Central region of human VAV1.

克隆位点

RB33825

亚型

Ig Fraction

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anti-Vav 1 Oncogene (VAV1) (Center) antibody
VAV1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Vav 1 Oncogene (VAV1) (Tyr174) antibody
VAV1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Vav 1 Oncogene (VAV1) (AA 100-200) antibody
VAV1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Vav 1 Oncogene (VAV1) (AA 426-696) antibody
VAV1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

VAV1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

有效期

6 months
抗原

VAV1 (Vav 1 Oncogene (VAV1))

别名

VAV1 (VAV1 产品)

别名

VAV antibody, Vav antibody, vav-T antibody, vav guanine nucleotide exchange factor 1 antibody, vav 1 oncogene antibody, vav guanine nucleotide exchange factor 1 L homeolog antibody, VAV1 antibody, Vav1 antibody, vav1.L antibody

背景

The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.

分子量

98314

基因ID

7409

NCBI登录号

NP_001245136, NP_005419

UniProt

P15498

途径

TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, BCR Signaling