NFE2 抗体 (C-Term)
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Quick Overview for NFE2 抗体 (C-Term) (ABIN657484)
抗原
See all NFE2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 312-340, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This NFE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 312-340 amino acids from the C-terminal region of human NFE2.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- NFE2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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有效期
- 6 months
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- NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))
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别名
- NFE2
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背景
- Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
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分子量
- 41473
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基因ID
- 4778
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NCBI登录号
- NP_001129495, NP_001248390, NP_006154
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UniProt
- Q16621
抗原
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