PACS2 抗体 (C-Term)
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Quick Overview for PACS2 抗体 (C-Term) (ABIN657066)
抗原
See all PACS2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 642-671, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This PACS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 642-671 amino acids from the C-terminal region of human PACS2.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- PACS2 (phosphofurin Acidic Cluster Sorting Protein 2 (PACS2))
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别名
- PACS2
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背景
- Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.
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分子量
- 97702
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NCBI登录号
- NP_001094383, NP_001230056, NP_056012
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UniProt
- Q86VP3
抗原
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