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SHANK2 抗体 (AA 879-908)

This 兔 多克隆 antibody specifically detects SHANK2 in WB. It exhibits reactivity toward 小鼠.It has been mentioned in 1 publication
产品编号 ABIN656710
发货至: 中国
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Quick Overview for SHANK2 抗体 (AA 879-908) (ABIN656710)

抗原

See all SHANK2 抗体
SHANK2 (SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2))

适用

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小鼠

宿主

  • 41
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克隆类型

  • 44
  • 30
多克隆

标记

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This SHANK2 antibody is un-conjugated

应用范围

  • 63
  • 32
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Western Blotting (WB)

克隆位点

RB31120
  • 抗原表位

    • 27
    • 15
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    AA 879-908

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This SHANK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 879-908 amino acids from the Central region of human SHANK2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    SHANK2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • de Sena Cortabitarte, Berkel, Cristian, Fischer, Rappold: "A direct regulatory link between microRNA-137 and SHANK2: implications for neuropsychiatric disorders." in: Journal of neurodevelopmental disorders, Vol. 10, Issue 1, pp. 15, (2018) (PubMed).

  • 抗原

    SHANK2 (SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2))

    别名

    SHANK2

    背景

    This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alpha motif domain, and a proline-rich region. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain. Two alternative splice variants, encoding distinct isoforms, are reported. Additional splice variants exist but their full-length nature has not been determined. [provided by RefSeq].

    分子量

    158822

    基因ID

    22941

    NCBI登录号

    NP_036441

    UniProt

    Q9UPX8
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