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DVL1 抗体 (AA 442-470)

Name: DVL1 抗体 (AA 442-470)
SKU: ABIN656260
Availability: OutOfStock

DVL1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB31716 unconjugated

DVL1 Antibody (Center) (ABIN656260 and ABIN2845574) western blot analysis in MDA-M cell line lysates (35 μg/lane).

IHC (p)

Confocal immunofluorescent analysis of DVL1 Antibody (Center) (ABIN656260 and ABIN2845574) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).

Immunofluorescent analysis of 4 % paraformaldehyde-fixed, 0.

All lanes : Anti-DVL1 Antibody (Center) at 1:2000 dilution Lane 1: K562 whole cell lysates Lane 2: MDA-MB-453 whole cell lysates Lane 3: PC-3 whole cell lysates Lane 4: human kidney lysates Lysates/proteins at 20 μg per lane.

Anti-DVL1 Antibody (Center)at 1:1000 dilution + PC-3 whole cell lysates Lysates/proteins at 20 μg per lane.

DVL1 Antibdy (Center) (ABIN656260 and ABIN2845574) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

IHC (p)

7 images

(1 reference)

产品编号 ABIN656260

发货至: 中国

Datasheet as PDF

抗原 See all DVL1 抗体

DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))
抗原表位
16

7

7

6

6

3

3

2

1

1

1

1

1

1

1

1

1
AA 442-470
适用
43

23

21

3

3

3

2

2

2

1

1

1
人, 小鼠
宿主
41

2

2
兔
Compatible Secondaries
克隆类型
45
多克隆
标记
20

3

3

3

3

2

1

1

1

1

1

1

1

1

1

1

1
This DVL1 antibody is un-conjugated
应用范围
44

19

18

14

13

13

12

7

5

3

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

预测反应

Rat

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This DVL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 442-470 amino acids from the Central region of human DVL1.

克隆位点

RB31716

亚型

Ig Fraction

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anti-Dishevelled Segment Polarity Protein 1 (DVL1) (AA 150-285) antibody
DVL1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Dishevelled Segment Polarity Protein 1 (DVL1) (AA 20-32) antibody
Verified DVL1 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Dishevelled Segment Polarity Protein 1 (DVL1) (AA 510-640) antibody
DVL1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Dishevelled Segment Polarity Protein 1 (DVL1) (AA 1-110) antibody
DVL1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Dishevelled Segment Polarity Protein 1 (DVL1) (AA 1-444) antibody
DVL1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Dishevelled Segment Polarity Protein 1 (DVL1) (Internal Region) antibody
Verified DVL1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Dishevelled Segment Polarity Protein 1 (DVL1) (AA 1-444) antibody
DVL1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Dishevelled Segment Polarity Protein 1 (DVL1) (AA 70-120) antibody
DVL1 适用: 人, 小鼠, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated

anti-Dishevelled Segment Polarity Protein 1 (DVL1) (AA 569-618) antibody
DVL1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated

应用备注

IF: 1:10~50. IF: 1:25. WB: 1:1000. WB: 1:2000. WB: 1:1000. IHC-P: 1:10~50. IHC-P: 1:25

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Bunn, Daniel, Rösken, ONeill, Cameron-Christie, Morgan, Brunner, Lai, Kunst, Markie, Robertson: "Mutations in DVL1 cause an osteosclerotic form of Robinow syndrome." in: American journal of human genetics, Vol. 96, Issue 4, pp. 623-30, (2015) (PubMed).
抗原

DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))

别名

DVL1 (DVL1 产品)

别名

DVL antibody, DVL1L1 antibody, DVL1P1 antibody, Dvl antibody, mKIAA4029 antibody, dvl-1 antibody, DSH antibody, DVL-1 antibody, dvl1 antibody, dvl2l antibody, Xdsh antibody, dsh1 antibody, dishevelled segment polarity protein 1 antibody, dishevelled, dsh homolog 1 (Drosophila) antibody, microRNA 6808 antibody, dishevelled segment polarity protein 1b antibody, dishevelled segment polarity protein 1 L homeolog antibody, DVL1 antibody, Dvl1 antibody, MIR6808 antibody, dvl1b antibody, dvl1.L antibody

背景

DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.

分子量

75187

基因ID

1855

NCBI登录号

NP_004412

UniProt

O14640

途径

WNT signaling, Synaptic Membrane, Skeletal Muscle Fiber Development