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RECQL2 抗体 (AA 787-816)

WRN 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB17383 unconjugated
产品编号 ABIN656017
发货至: 中国
  • 抗原 See all RECQL2 (WRN) 抗体
    RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))
    抗原表位
    • 7
    • 7
    • 7
    • 7
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 787-816
    适用
    • 41
    • 2
    • 1
    宿主
    • 34
    • 7
    克隆类型
    • 34
    • 7
    多克隆
    标记
    • 24
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RECQL2 antibody is un-conjugated
    应用范围
    • 31
    • 21
    • 12
    • 7
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This WRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 787-816 amino acids from the Central region of human WRN.
    克隆位点
    RB17383
    亚型
    Ig Fraction
    Top Product
    Discover our top product WRN Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:100. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Kawakubo-Yasukochi, Morioka, Hazekawa, Yasukochi, Nishinakagawa, Ono, Kawano, Nakamura, Nakashima: "miR-200c-3p spreads invasive capacity in human oral squamous cell carcinoma microenvironment." in: Molecular carcinogenesis, Vol. 57, Issue 2, pp. 295-302, (2018) (PubMed).

  • 抗原
    RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))
    别名
    WRN (WRN 产品)
    背景
    This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging.
    分子量
    162461
    基因ID
    7486
    NCBI登录号
    NP_000544
    UniProt
    Q14191
    途径
    DNA Damage Repair
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