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Glomulin, FKBP Associated Protein (GLMN) (AA 498-525), (C-Term) 抗体

ABIN655986 产品详细信息, 供应商: Log in to see
抗原
  • MGC69174
  • GLMN
  • FAP
  • FAP48
  • FAP68
  • FKBPAP
  • GLML
  • GVM
  • VMGLOM
  • 9330160J16Rik
  • AW227515
  • Fap48
  • Fap68
  • glomulin, FKBP associated protein
  • glmn
  • GLMN
  • Glmn
Alternatives
anti-人 Glomulin, FKBP Associated Protein 抗体 for ELISA
抗原表位
AA 498-525, C-Term
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2
1
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1
适用

68
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25
4
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宿主

54
16
克隆类型 (克隆位点)
多克隆 ()
标记
非结合性
4
4
4
3
3
3
1
1
1
1
1
1
1
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应用范围
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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30
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13
9
9
4
4
1
1
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免疫原 This GLMN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-525 AA from the C-terminal region of human GLMN.
克隆位点 RB31988
亚型 Ig
特异性 This GLMN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 505-533 amino acids from the C-terminal region of human GLMN.
预测反应 Mouse (Murine)
纯化方法 This antibody is purified through a protein A column, followed by peptide affinity purification.
别名 GLMN (GLMN Antibody 摘要)
背景 This gene encodes a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development of the vasculature and mutations in this gene have been associated with glomuvenous malformations, also called glomangiomas. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined. [provided by RefSeq].
Synonyms: GLMN,Glomulin,FAP48, FAP68, VMGLOM
分子量 68208 DA
基因ID 11146
NCBI登录号 NP_444504
UniProt Q92990
研究领域 Signaling, Phospho-specific antibodies, Protein Modifications, Cell Structure
途径 Tube Formation
应用备注 WB = 1:1000, IHC (p) = 1:10-50, FACS = 1:10-50
限制 仅限研究用
状态 Liquid
浓度 0.5 mg/mL
缓冲液 PBS with 0.09 % (W/V) sodium azide
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C/-20 °C
储存方法 Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期 6 months
厂商提供的图像
Western Blotting (WB) image for anti-Glomulin, FKBP Associated Protein (GLMN) (AA 498-525), (C-Term) 抗体 (ABIN655986) GLMN Antibody (C-term) western blot analysis in MDA-MB231,HepG2 cell line lysates (3...
Immunohistochemistry (IHC) image for anti-Glomulin, FKBP Associated Protein (GLMN) (AA 498-525), (C-Term) 抗体 (ABIN655986) GLMN Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin e...
Flow Cytometry (FACS) image for anti-Glomulin, FKBP Associated Protein (GLMN) (AA 498-525), (C-Term) 抗体 (ABIN655986) GLMN Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) comp...
背景 Arai, Kasper, Skaar, Ali, Takahashi, DeCaprio: "Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 17, pp. 9855-60, 2003 (PubMed).

Brouillard, Vikkula: "Vascular malformations: localized defects in vascular morphogenesis." in: Clinical genetics, Vol. 63, Issue 5, pp. 340-51, 2003 (PubMed).

Krummrei, Baulieu, Chambraud: "The FKBP-associated protein FAP48 is an antiproliferative molecule and a player in T cell activation that increases IL2 synthesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 5, pp. 2444-9, 2003 (PubMed).

Brouillard, Boon, Mulliken, Enjolras, Ghassibé, Warman, Tan, Olsen, Vikkula: "Mutations in a novel factor, glomulin, are responsible for glomuvenous malformations ("glomangiomas")." in: American journal of human genetics, Vol. 70, Issue 4, pp. 866-74, 2002 (PubMed).

Grisendi, Chambraud, Gout, Comoglio, Crepaldi: "Ligand-regulated binding of FAP68 to the hepatocyte growth factor receptor." in: The Journal of biological chemistry, Vol. 276, Issue 49, pp. 46632-8, 2001 (PubMed).