KLLN 抗体 (C-Term)
This 兔 多克隆 antibody specifically detects KLLN in WB. It exhibits reactivity toward 人. It has been mentioned in 3+ publications
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(3 references)
产品编号 ABIN655558
发货至:
中国
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Quick Overview for KLLN 抗体 (C-Term) (ABIN655558)
抗原
See all KLLN 抗体
KLLN
(Killin, p53-Regulated DNA Replication Inhibitor (KLLN))
适用
人
宿主
兔
克隆类型
多克隆
标记
This KLLN antibody is un-conjugated
应用范围
Western Blotting (WB)
克隆位点
RB29503
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抗原表位
- AA 136-163, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This KILLIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-163 amino acids from the C-terminal region of human KILLIN.
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亚型
- Ig Fraction
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应用备注
- WB: 1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Nuclear KLLN expression associates with improved relapse-free survival for prostate carcinoma." in: Endocrine-related cancer, Vol. 21, Issue 4, pp. 579-86, (2014) (PubMed).
: "Activation of AR sensitizes breast carcinomas to NVP-BEZ235's therapeutic effect mediated by PTEN and KLLN upregulation." in: Molecular cancer therapeutics, Vol. 13, Issue 2, pp. 517-27, (2014) (PubMed).
: "Androgen receptor-induced tumor suppressor, KLLN, inhibits breast cancer growth and transcriptionally activates p53/p73-mediated apoptosis in breast carcinomas." in: Human molecular genetics, Vol. 22, Issue 11, pp. 2263-72, (2013) (PubMed).
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- KLLN (Killin, p53-Regulated DNA Replication Inhibitor (KLLN))
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别名
- KILLIN
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背景
- DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating TP53/p53-induced apoptosis. Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis. Has affinity to both double-and single-stranded DNA.
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分子量
- 19958
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基因ID
- 100144748
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NCBI登录号
- NP_001119521
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UniProt
- B2CW77
抗原
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