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- 抗原 See all KLLN 抗体
- KLLN (Killin, p53-Regulated DNA Replication Inhibitor (KLLN))
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抗原表位
- AA 136-163, C-Term
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KLLN antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This KILLIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-163 amino acids from the C-terminal region of human KILLIN.
- 克隆位点
- RB29503
- 亚型
- Ig Fraction
- Top Product
- Discover our top product KLLN Primary Antibody
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- 应用备注
- WB: 1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Nuclear KLLN expression associates with improved relapse-free survival for prostate carcinoma." in: Endocrine-related cancer, Vol. 21, Issue 4, pp. 579-86, (2014) (PubMed).
: "Activation of AR sensitizes breast carcinomas to NVP-BEZ235's therapeutic effect mediated by PTEN and KLLN upregulation." in: Molecular cancer therapeutics, Vol. 13, Issue 2, pp. 517-27, (2014) (PubMed).
: "Androgen receptor-induced tumor suppressor, KLLN, inhibits breast cancer growth and transcriptionally activates p53/p73-mediated apoptosis in breast carcinomas." in: Human molecular genetics, Vol. 22, Issue 11, pp. 2263-72, (2013) (PubMed).
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Nuclear KLLN expression associates with improved relapse-free survival for prostate carcinoma." in: Endocrine-related cancer, Vol. 21, Issue 4, pp. 579-86, (2014) (PubMed).
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- 抗原
- KLLN (Killin, p53-Regulated DNA Replication Inhibitor (KLLN))
- 别名
- KILLIN (KLLN 产品)
- 别名
- CWS4 antibody, KILLIN antibody, killin, p53-regulated DNA replication inhibitor antibody, KLLN antibody
- 背景
- DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating TP53/p53-induced apoptosis. Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis. Has affinity to both double-and single-stranded DNA.
- 分子量
- 19958
- 基因ID
- 100144748
- NCBI登录号
- NP_001119521
- UniProt
- B2CW77
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