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KLLN 抗体 (C-Term)

KLLN 适用: 人 WB 宿主: 兔 Polyclonal RB29503 unconjugated
产品编号 ABIN655558
发货至: 中国
  • 抗原 See all KLLN 抗体
    KLLN (Killin, p53-Regulated DNA Replication Inhibitor (KLLN))
    抗原表位
    • 7
    • 7
    • 7
    • 1
    • 1
    • 1
    AA 136-163, C-Term
    适用
    宿主
    • 25
    克隆类型
    • 25
    多克隆
    标记
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KLLN antibody is un-conjugated
    应用范围
    • 17
    • 14
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This KILLIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-163 amino acids from the C-terminal region of human KILLIN.
    克隆位点
    RB29503
    亚型
    Ig Fraction
    Top Product
    Discover our top product KLLN Primary Antibody
  • 应用备注
    WB: 1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Wang, Roma, Nolley, Abdul-Karim, Peehl, Eng: "Nuclear KLLN expression associates with improved relapse-free survival for prostate carcinoma." in: Endocrine-related cancer, Vol. 21, Issue 4, pp. 579-86, (2014) (PubMed).

    Wang, Yu, He, Romigh, Altemus, Eng: "Activation of AR sensitizes breast carcinomas to NVP-BEZ235's therapeutic effect mediated by PTEN and KLLN upregulation." in: Molecular cancer therapeutics, Vol. 13, Issue 2, pp. 517-27, (2014) (PubMed).

    Wang, He, Yu, Eng: "Androgen receptor-induced tumor suppressor, KLLN, inhibits breast cancer growth and transcriptionally activates p53/p73-mediated apoptosis in breast carcinomas." in: Human molecular genetics, Vol. 22, Issue 11, pp. 2263-72, (2013) (PubMed).

  • 抗原
    KLLN (Killin, p53-Regulated DNA Replication Inhibitor (KLLN))
    别名
    KILLIN (KLLN 产品)
    别名
    CWS4 antibody, KILLIN antibody, killin, p53-regulated DNA replication inhibitor antibody, KLLN antibody
    背景
    DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating TP53/p53-induced apoptosis. Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis. Has affinity to both double-and single-stranded DNA.
    分子量
    19958
    基因ID
    100144748
    NCBI登录号
    NP_001119521
    UniProt
    B2CW77
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