OPN-A,b (AA 14-40), (N-Term) 抗体
适用: 人
WB, IF, IHC (p)
宿主: 兔
Polyclonal
RB19160
unconjugated
(4 references)-
- 抗原
- OPN-A,b
- 抗原表位
- AA 14-40, N-Term
- 适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- 非结合性
-
应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This OPN-a/b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-40 amino acids from the N-terminal region of human OPN-a/b.
- 克隆位点
- RB19160
- 亚型
- Ig Fraction
-
-
- 应用备注
- IF: 1:25. WB: 1:1000. WB: 1:2000. WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
-
-
: "MicroRNA-127-5p regulates osteopontin expression and osteopontin-mediated proliferation of human chondrocytes." in: Scientific reports, Vol. 6, pp. 25032, (2018) (PubMed).
: "NEAT1/miR-181c Regulates Osteopontin (OPN)-Mediated Synoviocyte Proliferation in Osteoarthritis." in: Journal of cellular biochemistry, Vol. 118, Issue 11, pp. 3775-3784, (2018) (PubMed).
: "MALAT1/miR-127-5p Regulates Osteopontin (OPN)-Mediated Proliferation of Human Chondrocytes Through PI3K/Akt Pathway." in: Journal of cellular biochemistry, Vol. 119, Issue 1, pp. 431-439, (2018) (PubMed).
: "Osteopontin Promotes Expression of Matrix Metalloproteinase 13 through NF-κB Signaling in Osteoarthritis." in: BioMed research international, Vol. 2016, pp. 6345656, (2016) (PubMed).
-
: "MicroRNA-127-5p regulates osteopontin expression and osteopontin-mediated proliferation of human chondrocytes." in: Scientific reports, Vol. 6, pp. 25032, (2018) (PubMed).
-
- 抗原
- OPN-A,b
- 背景
- Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity (By similarity).
- 分子量
- 35423
- 基因ID
- 6696
- NCBI登录号
- NP_000573, NP_001035147, NP_001035149, NP_001238758, NP_001238759
- UniProt
- P10451
-
You are here:
