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DHCR7 抗体 (C-Term)

DHCR7 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB17942 unconjugated
产品编号 ABIN655399
发货至: 中国
  • 抗原 See all DHCR7 抗体
    DHCR7 (7-Dehydrocholesterol Reductase (DHCR7))
    抗原表位
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 437-463, C-Term
    适用
    • 30
    • 27
    • 14
    人, 小鼠
    宿主
    • 37
    • 1
    克隆类型
    • 37
    • 1
    多克隆
    标记
    • 11
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DHCR7 antibody is un-conjugated
    应用范围
    • 34
    • 19
    • 15
    • 13
    • 6
    • 5
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This DHCR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 437-463 amino acids from the C-terminal region of human DHCR7.
    克隆位点
    RB17942
    亚型
    Ig Fraction
  • 应用备注
    IF: 1:25. IF: 1:10~50. WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    DHCR7 (7-Dehydrocholesterol Reductase (DHCR7))
    别名
    DHCR7 (DHCR7 产品)
    别名
    7-Dhcr antibody, Xdhcr7 antibody, MGC64361 antibody, slos antibody, 7-STEROL DELTA7 REDUCTASE antibody, 7RED antibody, DELTA5 antibody, DWARF 5 antibody, F11F12.21 antibody, F11F12_21 antibody, LE antibody, LEPIDA antibody, PA antibody, PARVA antibody, ST7R antibody, STEROL DELTA7 REDUCTASE antibody, DKFZp468C1911 antibody, AA409147 antibody, SLOS antibody, xdhcr7 antibody, 7-dehydrocholesterol reductase antibody, 7-dehydrocholesterol reductase L homeolog antibody, Ergosterol biosynthesis ERG4/ERG24 family antibody, DHCR7 antibody, dhcr7 antibody, dhcr7.L antibody, DWF5 antibody, PAAG_04766 antibody, PITG_13128 antibody, VDBG_05423 antibody, MGYG_00712 antibody, TERG_00580 antibody, Dhcr7 antibody
    背景
    This gene encodes an enzyme that removes the C(7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is ubiquitously expressed and its transmembrane protein localizes to the endoplasmic reticulum membrane and nuclear outer membrane. Mutations in this gene cause Smith-Lemli-Opitz syndrome (SLOS), a syndrome that is metabolically characterized by reduced serum cholesterol levels and elevated serum 7-dehydrocholesterol levels and phenotypically characterized by mental retardation, facial dysmorphism, syndactyly of second and third toes, and holoprosencephaly in severe cases to minimal physical abnormalities and near-normal intelligence in mild cases. Alternative splicing results in multiple transcript variants that encode the same protein.
    分子量
    54489
    基因ID
    1717
    NCBI登录号
    NP_001157289, NP_001351
    UniProt
    Q9UBM7
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