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CASP5 抗体 (AA 162-191)

CASP5 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18988 unconjugated
产品编号 ABIN654898
发货至: 中国
  • 抗原 See all CASP5 抗体
    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
    抗原表位
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 162-191
    适用
    • 44
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 41
    • 3
    克隆类型
    • 33
    • 11
    多克隆
    标记
    • 27
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This CASP5 antibody is un-conjugated
    应用范围
    • 26
    • 15
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This CASP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-191 amino acids from the Central region of human CASP5.
    克隆位点
    RB18988
    亚型
    Ig Fraction
    Top Product
    Discover our top product CASP5 Primary Antibody
  • 应用备注
    WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
    别名
    CASP5 (CASP5 产品)
    别名
    ICE(rel)III antibody, ICEREL-III antibody, ICH-3 antibody, CASP5 antibody, caspase 5 antibody, caspase-5 antibody, CASP5 antibody, LOC100437308 antibody
    背景
    This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein, this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.
    分子量
    49736
    基因ID
    838
    NCBI登录号
    NP_001129581, NP_001129582, NP_001129584, NP_004338
    UniProt
    P51878
    途径
    Inflammasome
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