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CADM1 抗体 (N-Term)

CADM1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB22685 unconjugated
产品编号 ABIN654660
发货至: 中国
  • 抗原 See all CADM1 抗体
    CADM1 (Cell Adhesion Molecule 1 (CADM1))
    抗原表位
    • 16
    • 9
    • 9
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 66-94, N-Term
    适用
    • 55
    • 38
    • 27
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 52
    • 3
    • 2
    克隆类型
    • 55
    • 2
    多克隆
    标记
    • 28
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CADM1 antibody is un-conjugated
    应用范围
    • 56
    • 27
    • 18
    • 18
    • 14
    • 14
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This CADM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human CADM1.
    克隆位点
    RB22685
    亚型
    Ig Fraction
    Top Product
    Discover our top product CADM1 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    CADM1 (Cell Adhesion Molecule 1 (CADM1))
    别名
    CADM1 (CADM1 产品)
    别名
    BL2 antibody, IGSF4 antibody, IGSF4A antibody, NECL2 antibody, Necl-2 antibody, RA175 antibody, ST17 antibody, SYNCAM antibody, TSLC1 antibody, sTSLC-1 antibody, sgIGSF antibody, synCAM1 antibody, bl2 antibody, igsf4 antibody, igsf4a antibody, necl-2 antibody, necl2 antibody, ra175 antibody, sgigsf antibody, st17 antibody, stslc-1 antibody, syncam antibody, syncam1 antibody, tslc1 antibody, xnecl2 antibody, 2900073G06Rik antibody, 3100001I08Rik antibody, AI987920 antibody, Bl2 antibody, Igsf4 antibody, Igsf4a antibody, Necl2 antibody, RA175A antibody, RA175B antibody, RA175C antibody, RA175N antibody, SgIGSF antibody, SynCam antibody, Tslc1 antibody, SynCAM1 antibody, cell adhesion molecule 1 antibody, cell adhesion molecule 1 L homeolog antibody, CADM1 antibody, cadm1.L antibody, Cadm1 antibody
    背景
    Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca(2+)-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. May act as a synaptic cell adhesion molecule that drives synapse assembly. May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.
    分子量
    48509
    基因ID
    23705
    NCBI登录号
    NP_001091987, NP_055148
    UniProt
    Q9BY67
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Activated T Cell Proliferation
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