This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This TNFRSF14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-236 amino acids from the Central region of human TNFRSF14.
TNFRSF14 is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response.