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FAS 抗体 (AA 185-211)

Name: FAS 抗体 (AA 185-211)
SKU: ABIN652469
Availability: OutOfStock

FAS 适用: 人 WB, IF 宿主: 兔 Polyclonal RB21902 unconjugated

Western blot analysis of FAS (arrow) using rabbit polyclonal FAS Antibody (Center) (ABIN652469 and ABIN2842320).

Western blot analysis of FAS Antibody (Center) (ABIN652469 and ABIN2842320) in T47D cell line lysates (35 μg/lane).

Confocal immunofluorescent analysis of FAS Antibody (Center) (ABIN652469 and ABIN2842320) with T47D cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).

3 images

(2 references)

产品编号 ABIN652469

发货至: 中国

Datasheet as PDF

抗原 See all FAS 抗体

FAS (TNF Receptor Superfamily, Member 6 (FAS))
抗原表位
25

16

16

8

7

6

5

5

4

4

4

4

3

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 185-211
适用
213

67

62

19

6

4

2

2

1

1
人
宿主
158

89

4

2

1

1

1

1
兔
Compatible Secondaries
克隆类型
155

100

1
多克隆
标记
123

27

25

12

10

7

4

4

3

3

3

3

3

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1
This FAS antibody is un-conjugated
应用范围
164

117

74

65

36

35

30

26

26

20

19

9

8

6

5

4

4

2

2

2

2

1

1
Western Blotting (WB), Immunofluorescence (IF)

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This FAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-211 amino acids from the Central region of human FAS.

克隆位点

RB21902

亚型

Ig Fraction

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FAS 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

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FAS 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 5B4 unconjugated

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FAS 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1B6 unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 20-119) antibody
FAS 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2G3 unconjugated

应用备注

IF: 1:10~50. WB: 1:1000. WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Kamikubo, Kai, Tsuji-Naito, Akagawa: "β-Caryophyllene attenuates palmitate-induced lipid accumulation through AMPK signaling by activating CB2 receptor in human HepG2 hepatocytes." in: Molecular nutrition & food research, Vol. 60, Issue 10, pp. 2228-2242, (2017) (PubMed).

Fan, Yu, Chen, Chen, Chung, Cheng: "The decreased expression of peroxisome proliferator-activated receptors delta (PPARdelta) is reversed by digoxin in the heart of diabetic rats." in: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme, Vol. 42, Issue 9, pp. 637-42, (2010) (PubMed).
抗原

FAS (TNF Receptor Superfamily, Member 6 (FAS))

别名

FAS (FAS 产品)

背景

FAS is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells.

分子量

37732

基因ID

355

NCBI登录号

NP_000034, NP_690610, NP_690611

UniProt

P25445

途径

p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity