PLEKHO1 抗体 (N-Term)
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- 抗原 See all PLEKHO1 抗体
- PLEKHO1 (Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1))
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抗原表位
- AA 49-77, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PLEKHO1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- B
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This CKIP-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-77 amino acids from the N-terminal region of human CKIP-1.
- 克隆位点
- RB19797
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PLEKHO1 Primary Antibody
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anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) antibody
PLEKHO1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 1-409) antibodyPLEKHO1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 51-170) antibodyPLEKHO1 适用: 人, 小鼠 ELISA, WB, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 143-404) antibodyPLEKHO1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 1-409) antibodyPLEKHO1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3D5 unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 1-409) antibodyPLEKHO1 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1C7 unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 1-410) antibodyPLEKHO1 适用: 人 ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1C7 unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (N-Term) antibodyPLEKHO1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (N-Term) antibodyPLEKHO1 适用: 人, 大鼠, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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- 抗原
- PLEKHO1 (Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1))
- 别名
- CKIP-1 (PLEKHO1 产品)
- 别名
- CKIP-1 antibody, OC120 antibody, 2810052M02Rik antibody, Ckip1 antibody, JZA-20 antibody, Jza2 antibody, RGD1311487 antibody, ckip-1 antibody, plekho1 antibody, si:dkey-200h23.2 antibody, pleckstrin homology domain containing O1 antibody, pleckstrin homology domain containing, family O member 1 antibody, pleckstrin homology domain containing, family O member 1a antibody, PLEKHO1 antibody, Plekho1 antibody, plekho1a antibody
- 背景
- CKIP-1 plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). This protein may function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). It appears to target ATM to the plasma membrane and appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation.
- 分子量
- 46237
- 基因ID
- 51177
- NCBI登录号
- NP_057358
- UniProt
- Q53GL0
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