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Metabotropic Glutamate Receptor 3 抗体 (C-Term)

GRM3 适用: 人 WB 宿主: 兔 Polyclonal RB4623 unconjugated
产品编号 ABIN652205
发货至: 中国
  • 抗原 See all Metabotropic Glutamate Receptor 3 (GRM3) 抗体
    Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))
    抗原表位
    • 16
    • 9
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 828-857, C-Term
    适用
    • 40
    • 31
    • 14
    • 11
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    宿主
    • 54
    • 2
    • 1
    克隆类型
    • 54
    • 3
    多克隆
    标记
    • 24
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Metabotropic Glutamate Receptor 3 antibody is un-conjugated
    应用范围
    • 44
    • 20
    • 17
    • 10
    • 10
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    Pr
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Metabotropic Glutamate Receptor 3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 828-857 amino acids from the C-terminal region of human Metabotropic Glutamate Receptor 3.
    克隆位点
    RB4623
    亚型
    Ig Fraction
    Top Product
    Discover our top product GRM3 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))
    别名
    Metabotropic Glutamate Receptor 3 (GPRC1C) (GRM3 产品)
    别名
    GLUR3 antibody, GPRC1C antibody, MGLUR3 antibody, mGlu3 antibody, 0710001G23Rik antibody, Gprc1c antibody, mGluR3 antibody, glutamate metabotropic receptor 3 antibody, glutamate receptor, metabotropic 3 antibody, GRM3 antibody, Grm3 antibody
    背景
    L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 (also known as GPRC1C) while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The activity of GRM3 is mediated by a G-protein that inhibits adenylate cyclase activity.
    分子量
    98879
    基因ID
    2913
    NCBI登录号
    NP_000831
    UniProt
    Q14832
    途径
    cAMP Metabolic Process, Synaptic Membrane
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