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IL-4 抗体 (C-Term)

Name: IL-4 抗体 (C-Term)
SKU: ABIN651434
Availability: OutOfStock

IL4 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22885 unconjugated

(LEFT)Western blot analysis of IL4 Antibody (C-term) (ABIN651434 and ABIN2840238) in WiDr cell line lysates (35 μg/lane).

IL4 Antibody (C-term) (ABIN651434 and ABIN2840238) IHC analysis in formalin fixed and paraffin embedded tonsil followed by peroxidase conjugation of the secondary antibody and DAB staining.

IHC (p)

IL4 Antibody (C-term) (ABIN651434 and ABIN2840238) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).

FACS

3 images

(2 references)

产品编号 ABIN651434

发货至: 中国

Datasheet as PDF

抗原 See all IL-4 (IL4) 抗体

IL-4 (IL4) (Interleukin 4 (IL4))
抗原表位
18

9

6

6

5

5

4

4

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 122-150, AA 122-151, C-Term
适用
134

56

22

14

11

10

10

8

7

5

5

4

3

3

3

3

2

2

1
人, 小鼠
宿主
108

59

56

7

3

2
兔
Compatible Secondaries
克隆类型
126

106

1
多克隆
标记
137

33

16

13

10

8

2

2

2

2

2

2

2

1

1

1

1

1
This IL-4 antibody is un-conjugated
应用范围
117

110

70

60

25

20

19

16

13

13

12

11

9

9

6

4

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

预测反应

Pr, Sh

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This L4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-150 amino acids from the C-terminal region of human L4.

克隆位点

RB22885

亚型

Ig Fraction

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anti-Interleukin 4 (IL4) antibody (Biotin)
IL4 适用: 小鼠 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin

应用备注

WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Zhang, Song, Wang, Wang, Zeng, Zhai, Ma, Li, Liao, Wang, Zhen, Wang, Cao, Lin, Ning, Liu: "Nasal IL-4(+)CXCR5(+)CD4(+) T follicular helper cell counts correlate with local IgE production in eosinophilic nasal polyps." in: The Journal of allergy and clinical immunology, Vol. 137, Issue 2, pp. 462-73, (2016) (PubMed).

Zhong, Zhou, Wu, Guo, Tan, Zhang, Zhang, Geng, Pan, Luo, Zhang, Xu, Liu, Liu, Gao, Liu, Ren, Li, Zhou, Zhang: "A SnoRNA-derived piRNA interacts with human interleukin-4 pre-mRNA and induces its decay in nuclear exosomes." in: Nucleic acids research, Vol. 43, Issue 21, pp. 10474-91, (2015) (PubMed).
抗原

IL-4 (IL4) (Interleukin 4 (IL4))

别名

IL4 (IL4 产品)

别名

IL4 antibody, IL-4 antibody, BCGF-1 antibody, BCGF1 antibody, BSF-1 antibody, BSF1 antibody, Il-4 antibody, Il4e12 antibody, IL2 antibody, interleukin 4 antibody, IL4 antibody, Il4 antibody

背景

IL4 is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome.

分子量

17492

基因ID

3565

NCBI登录号

NP_000580, NP_758858

UniProt

P05112

途径

JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation