Caspase 3 抗体 (Cleaved-Asp175)
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- 抗原 See all Caspase 3 (CASP3) 抗体
- Caspase 3 (CASP3)
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抗原表位
- AA 149-175, Cleaved-Asp175
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Caspase 3 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Dot Blot (DB)
- 预测反应
- B, M, Pig, Rat
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This Cleaved antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-175 amino acids from human Cleaved.
- 克隆位点
- RB25833
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CASP3 Primary Antibody
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- 应用备注
- IHC-P: 1:50~100. DB: 1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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The long noncoding RNA ASNR regulates degradation of Bcl-2 mRNA through its interaction with AUF1." in: Scientific reports, Vol. 6, pp. 32189, (2018) (PubMed).
: "Functional Characterization of Long Noncoding RNA Lnc_bc060912 in Human Lung Carcinoma Cells." in: Biochemistry, Vol. 54, Issue 18, pp. 2895-902, (2015) (PubMed).
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The long noncoding RNA ASNR regulates degradation of Bcl-2 mRNA through its interaction with AUF1." in: Scientific reports, Vol. 6, pp. 32189, (2018) (PubMed).
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- 抗原
- Caspase 3 (CASP3)
- 别名
- CASP3 (CASP3 产品)
- 别名
- CPP32 antibody, CPP32B antibody, SCA-1 antibody, A830040C14Rik antibody, AC-3 antibody, Apopain antibody, CC3 antibody, Caspase-3 antibody, Lice antibody, Yama antibody, mldy antibody, xcpp32 antibody, casp3 antibody, zgc:100890 antibody, CASP-3 antibody, caspase-3 antibody, caspase 3 antibody, caspase 3 S homeolog antibody, caspase 3, apoptosis-related cysteine peptidase a antibody, caspase 3, apoptosis-related cysteine peptidase antibody, CASP3 antibody, Casp3 antibody, casp3.S antibody, casp3a antibody
- 背景
- CASP3 encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.
- 分子量
- 31608
- 基因ID
- 836
- NCBI登录号
- NP_004337, NP_116786
- UniProt
- P42574
- 途径
- Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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