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FASL 抗体 (FITC)

FASL 适用: 小鼠, 大鼠 FACS 宿主: 仓鼠 Monoclonal MFL4 FITC
产品编号 ABIN614573
发货至: 中国
  • 抗原 See all FASL 抗体
    FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
    适用
    • 97
    • 47
    • 34
    • 18
    • 6
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    • 1
    小鼠, 大鼠
    宿主
    • 68
    • 28
    • 10
    • 5
    • 4
    • 1
    仓鼠
    克隆类型
    • 75
    • 41
    单克隆
    标记
    • 66
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    • 1
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    • 1
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    This FASL antibody is conjugated to FITC
    应用范围
    • 78
    • 53
    • 26
    • 22
    • 21
    • 17
    • 13
    • 13
    • 10
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    • 5
    • 5
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    Flow Cytometry (FACS)
    特异性
    Recognizes both Mouse and Rat CD178. Clone MFL4 is reported to block CD178/CD95 induced apoptosis. We recommend the use of AM20860LE-N for functional studies.
    纯化方法
    Affinity Chromatography on Protein G
    免疫原
    B6 Mouse FasL/BHK cells.
    克隆位点
    MFL4
    亚型
    IgG
    Top Product
    Discover our top product FASL Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light.
  • 抗原
    FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
    别名
    CD178 / Fas Ligand (FASL 产品)
    别名
    ALPS1B antibody, APT1LG1 antibody, APTL antibody, CD178 antibody, CD95-L antibody, CD95L antibody, FASL antibody, TNFSF6 antibody, fasl antibody, Fas-L antibody, Faslg antibody, Tnfsf6 antibody, gld antibody, Apt1Lg1 antibody, Fasl antibody, FASLG antibody, zgc:162027 antibody, Fas ligand antibody, Fas ligand L homeolog antibody, Fas ligand (TNF superfamily, member 6) antibody, FASLG antibody, faslg.L antibody, Fasl antibody, Faslg antibody, faslg antibody
    背景
    CD178, otherwise known as Fas Ligand/ CD95L, a 40 kDa type II transmembrane glycoprotein and member of the TNF/NGF superfamily, expressed by activated T cells and NK cells, which can be induced on a variety of cells by radiation, heat shock, chemotherapeutic agents and viral infection. CD178 acts as a key effector of cytotoxicity and in the regulation of immune responses. The binding of CD178 to its receptor CD95 (Fas), induces Fas-mediated apoptosis of target cells, and may be involved in the induction of peripheral tolerance and neutrophil chemotaxis. The binding of decoy receptor 3 (DcR3) to CD178 has been shown to inhibit CD178-mediated apoptosis.Synonyms: APT1LG1, APTL, Apoptosis antigen ligand, CD95L protein, FASL, FASLG, Fas antigen ligand, TNFSF6, Tumor necrosis factor ligand superfamily member 6
    基因ID
    14103
    NCBI登录号
    NP_034307
    UniProt
    P41047
    途径
    Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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